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    HEY2 hes related family bHLH transcription factor with YRPW motif 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712988, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HEY2provided by VGNC
    Official Full Name
    hes related family bHLH transcription factor with YRPW motif 2provided by VGNC
    Primary source
    VGNC:VGNC:73369
    See related
    Ensembl:ENSMMUG00000053773
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HEY2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (29268992..29280971)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (141886835..141898515, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114677481 Neighboring gene TPD52 like 1 Neighboring gene uncharacterized LOC114677482 Neighboring gene HD domain containing 2 Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene nuclear receptor coactivator 7 Neighboring gene cell division control protein 42 homolog pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anterior/posterior pattern specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in circulatory system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hairy/enhancer-of-split related with YRPW motif protein 2
    Names
    hairy/enhancer-of-split related with YRPW motif 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194380.3 → NP_001181309.1  hairy/enhancer-of-split related with YRPW motif protein 2

      See identical proteins and their annotated locations for NP_001181309.1

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000336
      UniProtKB/TrEMBL
      H9EU40
      Related
      ENSMMUP00000063630.1, ENSMMUT00000085434.1
      Conserved Domains (2) summary
      smart00511
      Location:119 → 165
      ORANGE; Orange domain
      cd18920
      Location:40 → 121
      bHLH-O_HEY2; basic helix-loop-helix-orange (bHLH-O) domain found in hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) and similar proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      29268992..29280971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015137303.2 → XP_014992789.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1

      UniProtKB/TrEMBL
      F6YUA8
      Conserved Domains (2) summary
      smart00511
      Location:73 → 119
      ORANGE; Orange domain
      cl00081
      Location:1 → 75
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. XM_015137304.2 → XP_014992790.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1

      UniProtKB/TrEMBL
      F6YUA8
      Conserved Domains (2) summary
      smart00511
      Location:73 → 119
      ORANGE; Orange domain
      cl00081
      Location:1 → 75
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials