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    HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703108, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HERC3provided by VGNC
    Official Full Name
    HECT and RLD domain containing E3 ubiquitin protein ligase 3provided by VGNC
    Primary source
    VGNC:VGNC:73365
    Locus tag
    EGK_15915
    See related
    Ensembl:ENSMMUG00000010138
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HERC3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (86972867..87095260)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (86992126..87114234)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene leukocyte surface antigen CD53 pseudogene Neighboring gene nuclear receptor coactivator 4 pseudogene Neighboring gene PIGY upstream open reading frame Neighboring gene phosphatidylinositol glycan anchor biosynthesis class Y Neighboring gene nucleosome assembly protein 1 like 5 Neighboring gene family with sequence similarity 13 member A Neighboring gene ubiquitin-60S ribosomal protein L40 pseudogene Neighboring gene 40S ribosomal protein S4, Y-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable E3 ubiquitin-protein ligase HERC3
    Names
    Putative E3 ubiquitin-protein ligase HERC3
    hect domain and RLD 3
    NP_001248295.1
    XP_014994233.1
    XP_014994234.1
    XP_028703911.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261366.1 → NP_001248295.1  probable E3 ubiquitin-protein ligase HERC3

      See identical proteins and their annotated locations for NP_001248295.1

      Status: PROVISIONAL

      Source sequence(s)
      JU470555
      UniProtKB/TrEMBL
      A0A8J8XN16, F6QY96, G7MTD8
      Related
      ENSMMUP00000013259.2, ENSMMUT00000014157.4
      Conserved Domains (3) summary
      COG5184
      Location:2 → 331
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:702 → 1048
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam00415
      Location:313 → 377
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      86972867..87095260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015138747.2 → XP_014994233.1  probable E3 ubiquitin-protein ligase HERC3 isoform X1

      UniProtKB/TrEMBL
      A0A8J8XN16, F6QY96, G7MTD8
      Conserved Domains (3) summary
      COG5184
      Location:2 → 331
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:702 → 1048
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam00415
      Location:313 → 377
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    2. XM_015138748.2 → XP_014994234.1  probable E3 ubiquitin-protein ligase HERC3 isoform X1

      UniProtKB/TrEMBL
      A0A8J8XN16, F6QY96, G7MTD8
      Conserved Domains (3) summary
      COG5184
      Location:2 → 331
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:702 → 1048
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam00415
      Location:313 → 377
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    3. XM_028848078.1 → XP_028703911.1  probable E3 ubiquitin-protein ligase HERC3 isoform X1

      UniProtKB/TrEMBL
      A0A8J8XN16, F6QY96, G7MTD8
      Conserved Domains (3) summary
      COG5184
      Location:2 → 331
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:702 → 1048
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam00415
      Location:313 → 377
      RCC1; Regulator of chromosome condensation (RCC1) repeat
    Nucleotide Protein
    Heading Accession and Version

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