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    Mlip muscular LMNA-interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 69642, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Mlipprovided by MGI
    Official Full Name
    muscular LMNA-interacting proteinprovided by MGI
    Primary source
    MGI:MGI:1916892
    See related
    Ensembl:ENSMUSG00000032355 AllianceGenome:MGI:1916892
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CIP; 2310046A06Rik
    Summary
    Enables lamin binding activity and transcription corepressor activity. Involved in negative regulation of cardiac muscle hypertrophy in response to stress. Acts upstream of or within negative regulation of cardiac muscle hypertrophy and negative regulation of transcription by RNA polymerase II. Located in PML body; nuclear envelope; and sarcolemma. Is expressed in frontal suture frontal osteogenic front. Orthologous to human MLIP (muscular LMNA interacting protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in heart adult (RPKM 11.7), cortex adult (RPKM 7.1) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mlip in Genome Data Viewer
    Location:
    9 D; 9 42.67 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (77009366..77260062, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (77102084..77352782, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene tubulointerstitial nephritis antigen Neighboring gene a disintegrin and metallopeptidase domain 4 pseudogene Neighboring gene STARR-seq mESC enhancer starr_24692 Neighboring gene STARR-seq mESC enhancer starr_24693 Neighboring gene STARR-seq mESC enhancer starr_24694 Neighboring gene STARR-seq mESC enhancer starr_24695 Neighboring gene predicted gene, 53504 Neighboring gene RIKEN cDNA 5730403I07 gene Neighboring gene STARR-positive B cell enhancer mm9_chr9:77234587-77234888 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:77317674-77317857 Neighboring gene STARR-seq mESC enhancer starr_24696 Neighboring gene STARR-seq mESC enhancer starr_24697 Neighboring gene leucine rich repeat containing 1 Neighboring gene STARR-seq mESC enhancer starr_24699

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression of murine muscle-enriched A-type lamin-interacting protein (MLIP) is regulated by tissue-specific alternative transcription start sites. Cattin ME, et al. J Biol Chem, 2018 Dec 21. PMID 30389785, Free PMC Article
    2. Cardiac ISL1-Interacting Protein, a Cardioprotective Factor, Inhibits the Transition From Cardiac Hypertrophy to Heart Failure. Yan Y, et al. Front Cardiovasc Med, 2022. PMID 35369338, Free PMC Article
    3. Cardiac CIP protein regulates dystrophic cardiomyopathy. He X, et al. Mol Ther, 2022 Feb 2. PMID 34400329, Free PMC Article
    4. Regulation of myonuclear positioning and muscle function by the skeletal muscle-specific CIP protein. Liu J, et al. Proc Natl Acad Sci U S A, 2020 Aug 11. PMID 32719146, Free PMC Article
    5. Identification of a novel muscle A-type lamin-interacting protein (MLIP). Ahmady E, et al. J Biol Chem, 2011 Jun 3. PMID 21498514, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cardiac CIP protein regulates dystrophic cardiomyopathy.
      Title: Cardiac CIP protein regulates dystrophic cardiomyopathy.
    2. Regulation of myonuclear positioning and muscle function by the skeletal muscle-specific CIP protein.
      Title: Regulation of myonuclear positioning and muscle function by the skeletal muscle-specific CIP protein.
    3. Mlip tissue-specific expression and alternative splicing play a critical role in determining MLIP's functions in mice
      Title: Expression of murine muscle-enriched A-type lamin-interacting protein (MLIP) is regulated by tissue-specific alternative transcription start sites.
    4. Deletion of the CIP-encoding gene accelerated progress from hypertrophy to heart failure in several cardiomyopathy models.
      Title: Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis.
    5. Mlip-deficient hearts showed an impaired capacity to adapt to stress (isoproterenol-induced hypertrophy), likely because of deregulated Akt/mTOR activity.
      Title: Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation.
    6. studies identify cardiac Isl1-interacting protein (CIP) as a novel regulator of cardiac hypertrophy.
      Title: CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy.
    7. MLIP is expressed most highly in striated and smooth muscle, it is likely to contribute to the mesenchymal phenotypes of laminopathies.
      Title: Identification of a novel muscle A-type lamin-interacting protein (MLIP).
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC107700

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lamin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription corepressor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of cardiac muscle hypertrophy IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of cardiac muscle hypertrophy in response to stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in PML body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear lumen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in sarcolemma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    muscular LMNA-interacting protein
    Names
    cardiac Isl1-interacting protein
    muscular-enriched A-type laminin-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368955.1 → NP_001355884.1  muscular LMNA-interacting protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (1) summary
      pfam15274
      Location:575 → 783
      MLIP; Muscular LMNA-interacting protein

    2. NM_001368956.1 → NP_001355885.1  muscular LMNA-interacting protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:451 → 663
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:596 → 807
      MLIP; Muscular LMNA-interacting protein

    3. NM_001368957.1 → NP_001355886.1  muscular LMNA-interacting protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (1) summary
      pfam15274
      Location:575 → 803
      MLIP; Muscular LMNA-interacting protein

    4. NM_001368958.1 → NP_001355887.1  muscular LMNA-interacting protein isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (1) summary
      pfam15274
      Location:575 → 783
      MLIP; Muscular LMNA-interacting protein

    5. NM_001368959.1 → NP_001355888.1  muscular LMNA-interacting protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (1) summary
      pfam15274
      Location:523 → 751
      MLIP; Muscular LMNA-interacting protein

    6. NM_001368960.1 → NP_001355889.1  muscular LMNA-interacting protein isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (1) summary
      pfam15274
      Location:581 → 761
      MLIP; Muscular LMNA-interacting protein

    7. NM_001368961.1 → NP_001355890.1  muscular LMNA-interacting protein isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Related
      ENSMUSP00000139055.2, ENSMUST00000184322.8
      Conserved Domains (2) summary
      PHA03307
      Location:451 → 663
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:596 → 827
      MLIP; Muscular LMNA-interacting protein

    8. NM_001368962.1 → NP_001355891.1  muscular LMNA-interacting protein isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (1) summary
      pfam15274
      Location:554 → 734
      MLIP; Muscular LMNA-interacting protein

    9. NM_001368963.1 → NP_001355892.1  muscular LMNA-interacting protein isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (1) summary
      pfam15274
      Location:575 → 803
      MLIP; Muscular LMNA-interacting protein

    10. NM_001368964.1 → NP_001355893.1  muscular LMNA-interacting protein isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:451 → 663
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:575 → 783
      MLIP; Muscular LMNA-interacting protein

    11. NM_001368965.1 → NP_001355894.1  muscular LMNA-interacting protein isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (1) summary
      pfam15274
      Location:529 → 709
      MLIP; Muscular LMNA-interacting protein

    12. NM_001368966.1 → NP_001355895.1  muscular LMNA-interacting protein isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (1) summary
      pfam15274
      Location:508 → 688
      MLIP; Muscular LMNA-interacting protein

    13. NM_001368967.1 → NP_001355896.1  muscular LMNA-interacting protein isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (1) summary
      pfam15274
      Location:554 → 734
      MLIP; Muscular LMNA-interacting protein

    14. NM_001368968.1 → NP_001355897.1  muscular LMNA-interacting protein isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (1) summary
      pfam15274
      Location:529 → 709
      MLIP; Muscular LMNA-interacting protein

    15. NM_001368969.1 → NP_001355898.1  muscular LMNA-interacting protein isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (1) summary
      pfam15274
      Location:581 → 761
      MLIP; Muscular LMNA-interacting protein

    16. NM_001368970.1 → NP_001355899.1  muscular LMNA-interacting protein isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      Conserved Domains (1) summary
      pfam15274
      Location:113 → 295
      MLIP; Muscular LMNA-interacting protein

    17. NM_001368971.1 → NP_001355900.1  muscular LMNA-interacting protein isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC123797, AC128705, AC151731
      Conserved Domains (1) summary
      pfam15274
      Location:113 → 271
      MLIP; Muscular LMNA-interacting protein

    18. NM_001368972.1 → NP_001355901.1  muscular LMNA-interacting protein isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXP3
      Related
      ENSMUSP00000139251.2, ENSMUST00000184415.8
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 373
      MLIP; Muscular LMNA-interacting protein

    19. NM_001368973.1 → NP_001355902.1  muscular LMNA-interacting protein isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 373
      MLIP; Muscular LMNA-interacting protein

    20. NM_001368974.1 → NP_001355903.1  muscular LMNA-interacting protein isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 349
      MLIP; Muscular LMNA-interacting protein

    21. NM_001368975.1 → NP_001355904.1  muscular LMNA-interacting protein isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 321
      MLIP; Muscular LMNA-interacting protein

    22. NM_001368976.1 → NP_001355905.1  muscular LMNA-interacting protein isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 297
      MLIP; Muscular LMNA-interacting protein

    23. NM_001368977.1 → NP_001355906.1  muscular LMNA-interacting protein isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 349
      MLIP; Muscular LMNA-interacting protein

    24. NM_001368978.1 → NP_001355907.1  muscular LMNA-interacting protein isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 279
      MLIP; Muscular LMNA-interacting protein

    25. NM_001368979.1 → NP_001355908.1  muscular LMNA-interacting protein isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 269
      MLIP; Muscular LMNA-interacting protein

    26. NM_001368980.1 → NP_001355909.1  muscular LMNA-interacting protein isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GX62
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 321
      MLIP; Muscular LMNA-interacting protein

    27. NM_001368981.1 → NP_001355910.1  muscular LMNA-interacting protein isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GX62
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 321
      MLIP; Muscular LMNA-interacting protein

    28. NM_001368982.1 → NP_001355911.1  muscular LMNA-interacting protein isoform 28

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GX62
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 301
      MLIP; Muscular LMNA-interacting protein

    29. NM_001368983.1 → NP_001355912.1  muscular LMNA-interacting protein isoform 29

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GX62
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 297
      MLIP; Muscular LMNA-interacting protein

    30. NM_001368984.1 → NP_001355913.1  muscular LMNA-interacting protein isoform 30

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 227
      MLIP; Muscular LMNA-interacting protein

    31. NM_001368985.1 → NP_001355914.1  muscular LMNA-interacting protein isoform 31

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Consensus CDS
      CCDS90630.1
      UniProtKB/TrEMBL
      V9GX62
      Related
      ENSMUSP00000139109.2, ENSMUST00000185039.8
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 279
      MLIP; Muscular LMNA-interacting protein

    32. NM_001368986.1 → NP_001355915.1  muscular LMNA-interacting protein isoform 33

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GX62
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 251
      MLIP; Muscular LMNA-interacting protein

    33. NM_001368987.1 → NP_001355916.1  muscular LMNA-interacting protein isoform 34

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GX62
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 249
      MLIP; Muscular LMNA-interacting protein

    34. NM_001368988.1 → NP_001355917.1  muscular LMNA-interacting protein isoform 35

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Consensus CDS
      CCDS90629.1
      UniProtKB/TrEMBL
      V9GX62
      Related
      ENSMUSP00000139242.2, ENSMUST00000184848.8
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 227
      MLIP; Muscular LMNA-interacting protein

    35. NM_001368989.1 → NP_001355918.1  muscular LMNA-interacting protein isoform 36

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 373
      MLIP; Muscular LMNA-interacting protein

    36. NM_027150.1 → NP_081426.1  muscular LMNA-interacting protein isoform 32

      See identical proteins and their annotated locations for NP_081426.1

      Status: VALIDATED

      Source sequence(s)
      AC116577, AC123797, AC128705, AC151731
      Consensus CDS
      CCDS52861.1
      UniProtKB/TrEMBL
      A2RRY2, V9GX62
      Related
      ENSMUSP00000034910.8, ENSMUST00000034910.16
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 269
      MLIP; Muscular LMNA-interacting protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      77009366..77260062 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155267.1 → XP_036011160.1  muscular LMNA-interacting protein isoform X24

      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 373
      MLIP; Muscular LMNA-interacting protein

    2. XM_036155273.1 → XP_036011166.1  muscular LMNA-interacting protein isoform X30

      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 373
      MLIP; Muscular LMNA-interacting protein

    3. XM_036155268.1 → XP_036011161.1  muscular LMNA-interacting protein isoform X25

      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 373
      MLIP; Muscular LMNA-interacting protein

    4. XM_036155275.1 → XP_036011168.1  muscular LMNA-interacting protein isoform X32

      Conserved Domains (1) summary
      pfam15274
      Location:121 → 349
      MLIP; Muscular LMNA-interacting protein

    5. XM_036155270.1 → XP_036011163.1  muscular LMNA-interacting protein isoform X27

      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:121 → 349
      MLIP; Muscular LMNA-interacting protein

    6. XM_036155276.1 → XP_036011169.1  muscular LMNA-interacting protein isoform X33

      UniProtKB/TrEMBL
      V9GX62
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 321
      MLIP; Muscular LMNA-interacting protein

    7. XM_036155272.1 → XP_036011165.1  muscular LMNA-interacting protein isoform X29

      UniProtKB/TrEMBL
      V9GXP3
      Conserved Domains (1) summary
      pfam15274
      Location:69 → 321
      MLIP; Muscular LMNA-interacting protein

    8. XM_036155260.1 → XP_036011153.1  muscular LMNA-interacting protein isoform X16

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:460 → 782
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:633 → 812
      MLIP; Muscular LMNA-interacting protein

    9. XM_036155274.1 → XP_036011167.1  muscular LMNA-interacting protein isoform X31

      Conserved Domains (1) summary
      pfam15274
      Location:174 → 332
      MLIP; Muscular LMNA-interacting protein

    10. XM_036155271.1 → XP_036011164.1  muscular LMNA-interacting protein isoform X28

      Conserved Domains (1) summary
      pfam15274
      Location:174 → 332
      MLIP; Muscular LMNA-interacting protein

    11. XM_036155269.1 → XP_036011162.1  muscular LMNA-interacting protein isoform X26

      Conserved Domains (1) summary
      pfam15274
      Location:174 → 332
      MLIP; Muscular LMNA-interacting protein

    12. XM_036155264.1 → XP_036011157.1  muscular LMNA-interacting protein isoform X21

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:512 → 792
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:724 → 822
      MLIP; Muscular LMNA-interacting protein

    13. XM_036155265.1 → XP_036011158.1  muscular LMNA-interacting protein isoform X22

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:512 → 724
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:685 → 846
      MLIP; Muscular LMNA-interacting protein

    14. XM_030244580.1 → XP_030100440.1  muscular LMNA-interacting protein isoform X11

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:512 → 724
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:716 → 846
      MLIP; Muscular LMNA-interacting protein

    15. XM_036155257.1 → XP_036011150.1  muscular LMNA-interacting protein isoform X6

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:512 → 724
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:685 → 868
      MLIP; Muscular LMNA-interacting protein

    16. XM_017313582.1 → XP_017169071.1  muscular LMNA-interacting protein isoform X20

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 817
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:774 → 847
      MLIP; Muscular LMNA-interacting protein

    17. XM_036155261.1 → XP_036011154.1  muscular LMNA-interacting protein isoform X17

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 817
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:749 → 847
      MLIP; Muscular LMNA-interacting protein

    18. XM_030244579.1 → XP_030100439.1  muscular LMNA-interacting protein isoform X10

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 817
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:774 → 847
      MLIP; Muscular LMNA-interacting protein

    19. XM_036155263.1 → XP_036011156.1  muscular LMNA-interacting protein isoform X19

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 808
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:710 → 869
      MLIP; Muscular LMNA-interacting protein

    20. XM_017313577.1 → XP_017169066.1  muscular LMNA-interacting protein isoform X15

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      pfam05110
      Location:663 → 813
      AF-4; AF-4 proto-oncoprotein
      pfam15274
      Location:774 → 889
      MLIP; Muscular LMNA-interacting protein

    21. XM_017313569.2 → XP_017169058.1  muscular LMNA-interacting protein isoform X7

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      pfam05110
      Location:663 → 813
      AF-4; AF-4 proto-oncoprotein
      pfam15274
      Location:774 → 889
      MLIP; Muscular LMNA-interacting protein

    22. XM_036155262.1 → XP_036011155.1  muscular LMNA-interacting protein isoform X18

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:710 → 871
      MLIP; Muscular LMNA-interacting protein

    23. XM_036155258.1 → XP_036011151.1  muscular LMNA-interacting protein isoform X9

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:710 → 871
      MLIP; Muscular LMNA-interacting protein

    24. XM_036155259.1 → XP_036011152.1  muscular LMNA-interacting protein isoform X14

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:710 → 893
      MLIP; Muscular LMNA-interacting protein

    25. XM_036155256.1 → XP_036011149.1  muscular LMNA-interacting protein isoform X5

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:710 → 893
      MLIP; Muscular LMNA-interacting protein

    26. XM_030244581.1 → XP_030100441.1  muscular LMNA-interacting protein isoform X12

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:741 → 913
      MLIP; Muscular LMNA-interacting protein

    27. XM_030244575.1 → XP_030100435.1  muscular LMNA-interacting protein isoform X3

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:741 → 913
      MLIP; Muscular LMNA-interacting protein

    28. XM_006511425.1 → XP_006511488.1  muscular LMNA-interacting protein isoform X13

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:741 → 898
      MLIP; Muscular LMNA-interacting protein

    29. XM_006511423.1 → XP_006511486.1  muscular LMNA-interacting protein isoform X8

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Related
      ENSMUSP00000139362.2, ENSMUST00000185144.8
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:741 → 941
      MLIP; Muscular LMNA-interacting protein

    30. XM_036155255.1 → XP_036011148.1  muscular LMNA-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:710 → 941
      MLIP; Muscular LMNA-interacting protein

    31. XM_006511414.1 → XP_006511477.1  muscular LMNA-interacting protein isoform X2

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:741 → 941
      MLIP; Muscular LMNA-interacting protein

    32. XM_006511411.1 → XP_006511474.1  muscular LMNA-interacting protein isoform X1

      UniProtKB/Swiss-Prot
      B7ZMP8, Q5FW52, Q9D6X9, V9GWW6
      Related
      ENSMUSP00000138864.2, ENSMUST00000183955.8
      Conserved Domains (2) summary
      PHA03307
      Location:537 → 749
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:741 → 941
      MLIP; Muscular LMNA-interacting protein

    33. XM_036155266.1 → XP_036011159.1  muscular LMNA-interacting protein isoform X23

      UniProtKB/TrEMBL
      V9GXA0
      Conserved Domains (2) summary
      PHA03307
      Location:460 → 672
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam15274
      Location:633 → 794
      MLIP; Muscular LMNA-interacting protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FW52.2 GenPept UniProtKB/Swiss-Prot:Q5FW52

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