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    Nol11 nucleolar protein 11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688885, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nol11provided by RGD
    Official Full Name
    nucleolar protein 11provided by RGD
    Primary source
    RGD:1584081
    See related
    EnsemblRapid:ENSRNOG00000052934 AllianceGenome:RGD:1584081
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in maturation of SSU-rRNA and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of t-UTP complex. Orthologous to human NOL11 (nucleolar protein 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 100.5), Thymus (RPKM 97.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Nol11 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (92621482..92641394, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (92119000..92141688, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (95388223..95408053, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene bromodomain PHD finger transcription factor Neighboring gene uncharacterized LOC120095194 Neighboring gene U11 spliceosomal RNA Neighboring gene actin, beta, pseudogene 10 Neighboring gene phosphatidylinositol transfer protein, cytoplasmic 1 Neighboring gene small nucleolar RNA, H/ACA box 80D

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in maturation of SSU-rRNA ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of t-UTP complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402074.1NP_001389003.1  nucleolar protein 11 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A0G2K1A9
      Related
      ENSRNOP00000071766.2, ENSRNOT00000077888.3
    2. NM_001402075.1NP_001389004.1  nucleolar protein 11 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      92621482..92641394 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)