Aldh3b3 aldehyde dehydrogenase 3 family, member B3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Aldh3b3provided by RGD
Official Full Name: aldehyde dehydrogenase 3 family, member B3provided by RGD
Primary source: RGD:1585230
See related: EnsemblRapid:ENSRNOG00000017872 AllianceGenome:RGD:1585230
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in cellular aldehyde metabolic process. Predicted to be located in cytoplasm; lipid droplet; and plasma membrane. Orthologous to human ALDH3B2 (aldehyde dehydrogenase 3 family member B2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 22.9), Lung (RPKM 14.4) and 9 other tissues See more
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Genomic context

Location:: 1q43

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (210617090..210629886)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (201193832..201201666)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (219193465..219207062)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 3-chloroallyl aldehyde dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables aldehyde dehydrogenase (NAD+) activity	IBA Inferred from Biological aspect of Ancestor more info
enables aldehyde dehydrogenase (NAD+) activity	ISO Inferred from Sequence Orthology more info
enables aldehyde dehydrogenase [NAD(P)+] activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in aldehyde metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in aldehyde metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in lipid droplet	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: aldehyde dehydrogenase 3 family, member B3; aldehyde dehydrogenase family 3 member B3

Names: aldehyde dehydrogenase family 3 member B1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001432596.1 → NP_001419525.1 aldehyde dehydrogenase 3 family, member B3

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

A0A8I6ACF4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

210617090..210629886

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039101314.2 → XP_038957242.2 aldehyde dehydrogenase family 3 member B3 isoform X1

Related

ENSRNOP00000024034.7, ENSRNOT00000024034.9
XM_039101315.2 → XP_038957243.1 aldehyde dehydrogenase family 3 member B3 isoform X2

Conserved Domains (1) summary

cl11961
Location:1 → 261

ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily