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    Bend3 BEN domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 683923, updated on 9-Dec-2024

    Summary

    Official Symbol
    Bend3provided by RGD
    Official Full Name
    BEN domain containing 3provided by RGD
    Primary source
    RGD:1596570
    See related
    EnsemblRapid:ENSRNOG00000046505 AllianceGenome:RGD:1596570
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable rDNA binding activity. Predicted to be involved in negative regulation of macromolecule biosynthetic process; positive regulation of ATP metabolic process; and protein homooligomerization. Predicted to be located in heterochromatin; nucleolus; and nucleoplasm. Orthologous to human BEND3 (BEN domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 26.0), Kidney (RPKM 23.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Bend3 in Genome Data Viewer
    Location:
    20q13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (48562383..48599194)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (46980246..47017059)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (48248193..48270905)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene decaprenyl diphosphate synthase subunit 2 Neighboring gene uncharacterized LOC102551730 Neighboring gene ribosomal protein L37A, pseudogene 5 Neighboring gene mitochondrial transcription rescue factor 1 Neighboring gene fractured callus expressed transcript 1, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables rDNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables rDNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in heterochromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    BEN domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      48562383..48599194
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099149.2XP_038955077.1  BEN domain-containing protein 3

      UniProtKB/TrEMBL
      A6K6X1, M0RCL1
      Related
      ENSRNOP00000067331.1, ENSRNOT00000071494.4
      Conserved Domains (1) summary
      smart01025
      Location:735814
      BEN; The BEN domain is found in diverse animal proteins