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    LOC6548717 myosin light chain kinase, smooth muscle [ Drosophila erecta ]

    Gene ID: 6548717, updated on 10-May-2024

    Summary

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    Gene symbol
    LOC6548717
    Gene description
    myosin light chain kinase, smooth muscle
    Locus tag
    Dere_GG22319
    See related
    EnsemblRapid:LOC6548717
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Drosophila erecta
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    GG22319; GG26907; GG22319-PA; GG22319-PB; GG22319-PC; GG22319-PD; GG22319-PE; GG22319-PF; GG22319-PG; GG26907-PA
    Orthologs
    fruit fly all
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    Genomic context

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    See LOC6548717 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    101 current DereRS2 (GCF_003286155.1) Unplaced Scaffold NW_020825207.1 (8777609..8809828, complement)

    NW_020825207.1Genomic Context describing neighboring genes Neighboring gene trypsin alpha-3 Neighboring gene Probable cytochrome P450 4aa1 Neighboring gene Cytochrome c oxidase subunit 6A-like Neighboring gene uncharacterized LOC6548718 Neighboring gene muscle M-line assembly protein unc-89 Neighboring gene palmitoyltransferase ZDHHC3 Neighboring gene peroxisomal membrane protein 11B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_020825207 Unplaced Scaffold Reference DereRS2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    muscle M-line assembly protein unc-89; myosin light chain kinase, smooth muscle; titin
    Names
    Dere\GG22319
    Dere\GG22319-PA
    Dere\GG22319-PB
    Dere\GG22319-PC
    Dere\GG22319-PD
    Dere\GG22319-PE
    Dere\GG22319-PF
    Dere\GG22319-PG
    Dere\GG26907
    Dere\GG26907-PA
    dere_GLEANR_7060

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Drosophila erecta Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference DereRS2

    Genomic

    1. NW_020825207.1 Reference DereRS2

      Range
      8777609..8809828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001975411.3 → XP_001975447.3  titin isoform X5

      Related
      XP_001975447.3, XM_001975411.3
      Conserved Domains (11) summary
      smart00409
      Location:5004 → 5069
      IG; Immunoglobulin
      smart00410
      Location:5333 → 5402
      IG_like; Immunoglobulin like
      cd00063
      Location:5416 → 5514
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:4371 → 4460
      I-set; Immunoglobulin I-set domain
      cd14103
      Location:5551 → 5801
      STKc_MLCK; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase
      pfam13927
      Location:3328 → 3406
      Ig_3; Immunoglobulin domain
      cd00096
      Location:3831 → 3892
      Ig; Immunoglobulin domain
      cl11960
      Location:4043 → 4116
      Ig; Immunoglobulin domain
      cl25732
      Location:567 → 1448
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26511
      Location:1062 → 1945
      Neuromodulin_N; Gap junction protein N-terminal region
      cl28434
      Location:4591 → 4683
      I-set; Immunoglobulin I-set domain

    2. XM_015156824.2 → XP_015012310.1  myosin light chain kinase, smooth muscle isoform X4

      UniProtKB/TrEMBL
      A0A0Q5VW91
      Related
      XP_015012310.1, XM_015156824.2
      Conserved Domains (4) summary
      smart00220
      Location:292 → 548
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      smart00410
      Location:80 → 149
      IG_like; Immunoglobulin like
      cd00063
      Location:163 → 261
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14103
      Location:298 → 548
      STKc_MLCK; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase

    3. XM_026980403.1 → XP_026836204.1  myosin light chain kinase, smooth muscle isoform X3

      UniProtKB/TrEMBL
      A0A0Q5W127
      Related
      XP_026836204.1, XM_026980403.1
      Conserved Domains (2) summary
      cd00063
      Location:19 → 117
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14103
      Location:154 → 404
      STKc_MLCK; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase

    4. XM_026980402.1 → XP_026836203.1  myosin light chain kinase, smooth muscle isoform X2

      Related
      XP_026836203.1, XM_026980402.1
      Conserved Domains (3) summary
      smart00410
      Location:82 → 151
      IG_like; Immunoglobulin like
      cd00063
      Location:165 → 263
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14103
      Location:300 → 550
      STKc_MLCK; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase

    5. XM_015156825.2 → XP_015012311.1  muscle M-line assembly protein unc-89 isoform X1

      UniProtKB/TrEMBL
      A0A0Q5VNF2, A0A0Q5VYC0
      Related
      XP_015012311.1, XM_015156825.2
      Conserved Domains (5) summary
      cd00096
      Location:1625 → 1689
      Ig; Immunoglobulin domain
      smart00408
      Location:828 → 893
      IGc2; Immunoglobulin C-2 Type
      cd00121
      Location:522 → 575
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam07679
      Location:1345 → 1428
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:1837 → 1910
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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