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    H2-K2 histocompatibility 2, K region locus 2 [ Mus musculus (house mouse) ]

    Gene ID: 630499, updated on 17-Aug-2024

    Summary

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    Official Symbol
    H2-K2provided by MGI
    Official Full Name
    histocompatibility 2, K region locus 2provided by MGI
    Primary source
    MGI:MGI:95906
    See related
    Ensembl:ENSMUSG00000121503 AllianceGenome:MGI:95906
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H-2K1; H-2K2; H2-K1; Gm7035; H-2K1K; EG630499
    Expression
    Broad expression in spleen adult (RPKM 73.6), liver adult (RPKM 63.2) and 17 other tissues See more
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    Genomic context

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    See H2-K2 in Genome Data Viewer
    Location:
    17 17.98 cM; 17 B1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (34193633..34197765, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (33974659..33978791, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8668 Neighboring gene ribosomal protein S18 Neighboring gene STARR-positive B cell enhancer ABC_E3199 Neighboring gene VPS52 GARP complex subunit Neighboring gene predicted gene, 23111 Neighboring gene STARR-positive B cell enhancer ABC_E2483 Neighboring gene STARR-seq mESC enhancer starr_42421 Neighboring gene predicted gene, 53998 Neighboring gene expressed sequence AA388235

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cloning and sequence analysis of the H2-K2(b) gene reveals that it is a pseudogene. Uzgare RP, et al. Immunogenetics, 1999 Oct. PMID 10541816
    2. Alternative pre-mRNA splicing of Kj eliminates a sequence that is unique to H-2K transcripts. Pogulis RJ, et al. Mol Immunol, 1994 Feb. PMID 8114769
    3. Inactivation of the H-2Klk gene could involve the substitutions of methylated CpGs. Sim BC, et al. J Immunogenet, 1990 Feb-Apr. PMID 2212699
    4. Mouse histocompatibility genes: structure and organisation of a Kd gene. Kvist S, et al. EMBO J, 1983. PMID 11894934, Free PMC Article
    5. Sequence analysis of the C3H H-2K1k gene: relationship to the H-2 loci. Watts S, et al. Immunogenetics, 1989. PMID 2714856

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • histocompatibility 2, K region locus 1
    • predicted pseudogene 7035

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_004446.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      CR974462
      Related
      ENSMUST00000241639.1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      34193633..34197765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_001378.1: Suppressed sequence

      Description
      NG_001378.1: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.

    2. NG_001378.1: Suppressed sequence

      Description
      NG_001378.1: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.

    3. NM_001081015.1: Suppressed sequence

      Description
      NM_001081015.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.