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    SCN9A sodium voltage-gated channel alpha subunit 9 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574119, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SCN9Aprovided by VGNC
    Official Full Name
    sodium voltage-gated channel alpha subunit 9provided by VGNC
    Primary source
    VGNC:VGNC:76990
    See related
    Ensembl:ENSMMUG00000018510
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    ENACH
    Orthologs
    human mouse all
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    Genomic context

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    See SCN9A in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (53352971..53536263, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (53132697..53313153, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671340 Neighboring gene tetratricopeptide repeat domain 21B Neighboring gene sodium voltage-gated channel alpha subunit 1 Neighboring gene uncharacterized LOC106992602 Neighboring gene L-lactate dehydrogenase B chain pseudogene Neighboring gene small nucleolar RNA U13 Neighboring gene sodium voltage-gated channel alpha subunit 7 Neighboring gene uncharacterized LOC106992604 Neighboring gene uncharacterized LOC114671342

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of an ovarian voltage-activated Na+-channel type: hints to involvement in luteolysis. Bulling A, et al. Mol Endocrinol, 2000 Jul. PMID 10894155
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuronal action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium channel protein type 9 subunit alpha
    Names
    sodium channel, voltage-gated, type IX, alpha subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      53352971..53536263 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028830806.1 → XP_028686639.1  sodium channel protein type 9 subunit alpha isoform X2

      UniProtKB/TrEMBL
      F7A8X1, G7N879
      Related
      ENSMMUP00000024352.4, ENSMMUT00000026025.4
      Conserved Domains (5) summary
      cd13433
      Location:1447 → 1499
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1180 → 1455
      Ion_trans; Ion transport protein
      pfam06512
      Location:971 → 1176
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:488 → 673
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1763 → 1826
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    2. XM_028830807.1 → XP_028686640.1  sodium channel protein type 9 subunit alpha isoform X3

      UniProtKB/TrEMBL
      G7N879
      Related
      ENSMMUP00000024354.4, ENSMMUT00000026027.4
      Conserved Domains (5) summary
      cd13433
      Location:1364 → 1416
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1420 → 1676
      Ion_trans; Ion transport protein
      pfam06512
      Location:982 → 1187
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:488 → 684
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1680 → 1743
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    3. XM_015110280.2 → XP_014965766.2  sodium channel protein type 9 subunit alpha isoform X1

      UniProtKB/TrEMBL
      G7N879
      Conserved Domains (5) summary
      cd13433
      Location:1458 → 1510
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1191 → 1466
      Ion_trans; Ion transport protein
      pfam06512
      Location:982 → 1187
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:488 → 684
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1774 → 1837
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    4. XM_028830805.1 → XP_028686638.1  sodium channel protein type 9 subunit alpha isoform X1

      UniProtKB/TrEMBL
      G7N879
      Related
      ENSMMUP00000051886.2, ENSMMUT00000076319.2
      Conserved Domains (5) summary
      cd13433
      Location:1458 → 1510
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1191 → 1466
      Ion_trans; Ion transport protein
      pfam06512
      Location:982 → 1187
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:488 → 684
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1774 → 1837
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    Nucleotide Protein
    Heading Accession and Version

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