U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    inavaa innate immunity activator a [ Danio rerio (zebrafish) ]

    Gene ID: 567844, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    inavaaprovided by ZNC
    Official Full Name
    innate immunity activator aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081105-161
    See related
    Ensembl:ENSDARG00000078155 AllianceGenome:ZFIN:ZDB-GENE-081105-161
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-163l21.4
    Summary
    Predicted to be involved in adherens junction maintenance and positive regulation of protein ubiquitination. Human ortholog(s) of this gene implicated in inflammatory bowel disease 29. Orthologous to human INAVA (innate immunity activator). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See inavaa in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (23753247..23775649, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (23732008..23754633, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene FA complementation group E Neighboring gene si:ch211-163l21.11 Neighboring gene ribosomal protein L10a Neighboring gene si:ch211-163l21.7 Neighboring gene zgc:195245

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in adherens junction maintenance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    innate immunity activator protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      23753247..23775649 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021478428.2 → XP_021334103.1  innate immunity activator protein

      UniProtKB/TrEMBL
      A0A8M9Q2R6, F1QAI0
      Related
      ENSDARP00000103134.3, ENSDART00000114800.4
      Conserved Domains (1) summary
      pfam11819
      Location:4 → 138
      DUF3338; Domain of unknown function (DUF3338)

    2. XM_021478429.2 → XP_021334104.1  innate immunity activator protein

      UniProtKB/TrEMBL
      A0A8M9Q2R6, F1QAI0
      Conserved Domains (1) summary
      pfam11819
      Location:4 → 138
      DUF3338; Domain of unknown function (DUF3338)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394724.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      12975..35377 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009303967.4 → XP_009302242.1  innate immunity activator protein

      UniProtKB/TrEMBL
      A0A8M9Q2R6, F1QAI0
      Conserved Domains (1) summary
      pfam11819
      Location:4 → 138
      DUF3338; Domain of unknown function (DUF3338)

    2. XM_021472065.2 → XP_021327740.1  innate immunity activator protein

      UniProtKB/TrEMBL
      A0A8M9Q2R6, F1QAI0
      Conserved Domains (1) summary
      pfam11819
      Location:4 → 138
      DUF3338; Domain of unknown function (DUF3338)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools