stxbp5l syntaxin binding protein 5L [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: stxbp5lprovided by ZNC
Official Full Name: syntaxin binding protein 5Lprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041210-220
See related: Ensembl:ENSDARG00000006383 AllianceGenome:ZFIN:ZDB-GENE-041210-220
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-194d6.1
Summary: Predicted to act upstream of or within exocytosis and protein transport. Predicted to be located in cytoplasm and plasma membrane. Orthologous to human STXBP5L (syntaxin binding protein 5L). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (27413722..27649371, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (27602974..27838635, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables myosin II binding	IBA Inferred from Biological aspect of Ancestor more info
enables syntaxin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in Golgi to plasma membrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within exocytosis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SNARE complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: syntaxin-binding protein 5-like

Names: syntaxin binding protein 5-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045137.1 → NP_001038602.1 syntaxin-binding protein 5-like

See identical proteins and their annotated locations for NP_001038602.1

Status: PROVISIONAL

Source sequence(s)

BX322637

UniProtKB/Swiss-Prot

Q5SQE2

Related

ENSDARP00000027152.9, ENSDART00000017292.10

Conserved Domains (5) summary

COG2319
Location:76 → 495

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1093 → 1152

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:290 → 397

LLGL; LLGL2

sd00039
Location:67 → 105

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 281

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007120.7 Reference GRCz11 Primary Assembly

Range

27413722..27649371 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021478738.2 → XP_021334413.1 syntaxin-binding protein 5-like isoform X10

UniProtKB/TrEMBL

A0A8M9Q4P1

Conserved Domains (4) summary

cd15893
Location:1103 → 1162

R-SNARE_STXBP5; SNARE domain of STXBP5

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

pfam08366
Location:282 → 389

LLGL; LLGL2

cl25539
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_021478740.2 → XP_021334415.1 syntaxin-binding protein 5-like isoform X15

UniProtKB/TrEMBL

A0A8M9QJS6

Conserved Domains (4) summary

cd15893
Location:1031 → 1090

R-SNARE_STXBP5; SNARE domain of STXBP5

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

pfam08366
Location:282 → 389

LLGL; LLGL2

cl25539
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_009304754.4 → XP_009303029.1 syntaxin-binding protein 5-like isoform X11

UniProtKB/TrEMBL

A0A2R8Q0L1, A0A8M3AW41

Related

ENSDARP00000147177.1, ENSDART00000187112.1

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1092 → 1151

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_009304752.4 → XP_009303027.1 syntaxin-binding protein 5-like isoform X7

UniProtKB/TrEMBL

A0A8M3AW43

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1125 → 1184

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_068223455.1 → XP_068079556.1 syntaxin-binding protein 5-like isoform X16
XM_005167727.5 → XP_005167784.1 syntaxin-binding protein 5-like isoform X3

UniProtKB/TrEMBL

A0A8M2BFT0

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1178 → 1237

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_021478739.2 → XP_021334414.1 syntaxin-binding protein 5-like isoform X14

UniProtKB/TrEMBL

A0A8M9QAW6

Conserved Domains (4) summary

cd15893
Location:1054 → 1113

R-SNARE_STXBP5; SNARE domain of STXBP5

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

pfam08366
Location:282 → 389

LLGL; LLGL2

cl25539
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_068223453.1 → XP_068079554.1 syntaxin-binding protein 5-like isoform X13
XM_009304753.4 → XP_009303028.1 syntaxin-binding protein 5-like isoform X8

UniProtKB/TrEMBL

A0A2R8QFD7, A0A8M3BCI2

Related

ENSDARP00000153693.1, ENSDART00000181270.1

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1115 → 1174

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_005167729.5 → XP_005167786.1 syntaxin-binding protein 5-like isoform X6

UniProtKB/TrEMBL

A0A8M2BF63

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1148 → 1207

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_021478737.2 → XP_021334412.1 syntaxin-binding protein 5-like isoform X5

UniProtKB/TrEMBL

A0A8M9PSA3

Conserved Domains (4) summary

cd15893
Location:1166 → 1225

R-SNARE_STXBP5; SNARE domain of STXBP5

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

pfam08366
Location:282 → 389

LLGL; LLGL2

cl25539
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_068223452.1 → XP_068079553.1 syntaxin-binding protein 5-like isoform X12
XM_005167726.5 → XP_005167783.1 syntaxin-binding protein 5-like isoform X2

UniProtKB/TrEMBL

A0A8M2BF49

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1183 → 1242

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_068223451.1 → XP_068079552.1 syntaxin-binding protein 5-like isoform X9
XM_005167728.5 → XP_005167785.1 syntaxin-binding protein 5-like isoform X4

UniProtKB/TrEMBL

A0A8M2BF66

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1168 → 1227

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_005167725.5 → XP_005167782.1 syntaxin-binding protein 5-like isoform X1

UniProtKB/TrEMBL

A0A8M2BF64

Conserved Domains (5) summary

COG2319
Location:67 → 471

WD40; WD40 repeat [General function prediction only]

cd15893
Location:1201 → 1260

R-SNARE_STXBP5; SNARE domain of STXBP5

pfam08366
Location:282 → 389

LLGL; LLGL2

sd00039
Location:67 → 103

7WD40; WD40 repeat [structural motif]

cl02567
Location:67 → 273

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...