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    etnk1 ethanolamine kinase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 565971, updated on 9-Dec-2024

    Summary

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    Official Symbol
    etnk1provided by ZNC
    Official Full Name
    ethanolamine kinase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030328-21
    See related
    Ensembl:ENSDARG00000019420 AllianceGenome:ZFIN:ZDB-GENE-030328-21
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb661; wu:fb38f12; wu:fj21d12; si:dkey-13i19.1
    Summary
    Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm. Is expressed in pronephric duct. Orthologous to human ETNK1 (ethanolamine kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See etnk1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (16885801..16906064)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (16896779..16916406)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene thymopoietin a Neighboring gene serine/threonine kinase receptor associated protein Neighboring gene uncharacterized LOC137491538 Neighboring gene SRY-box transcription factor 5 Neighboring gene uncharacterized LOC137491396

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Regulation of spermatogonial development by Fsh: The complementary roles of locally produced Igf and Wnt signaling molecules in adult zebrafish testis. Safian D, et al. Gen Comp Endocrinol, 2019 Dec 1. PMID 31415728
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ethanolamine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ethanolamine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphatidylethanolamine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ethanolamine kinase 1
    XP_009298589.1
    XP_689471.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      16885801..16906064
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_684379.10 → XP_689471.3  ethanolamine kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8N7T5U8, Q5RGY0
      Related
      ENSDARP00000019763.7, ENSDART00000017726.8
      Conserved Domains (1) summary
      cd05157
      Location:46 → 348
      ETNK_euk; Euykaryotic Ethanolamine kinase

    2. XM_009300314.4 → XP_009298589.1  ethanolamine kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M3ARF6, A0A8M3B8Z8
      Conserved Domains (1) summary
      cl21453
      Location:46 → 231
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version

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