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    mtmr9 myotubularin related protein 9 [ Danio rerio (zebrafish) ]

    Gene ID: 565063, updated on 4-Jan-2025

    Summary

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    Official Symbol
    mtmr9provided by ZNC
    Official Full Name
    myotubularin related protein 9provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040724-223
    See related
    Ensembl:ENSDARG00000015860 AllianceGenome:ZFIN:ZDB-GENE-040724-223
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-155d18.2
    Summary
    Predicted to enable protein phosphatase binding activity. Predicted to be involved in negative regulation of autophagy and phosphatidylinositol dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human MTMR9 (myotubularin related protein 9). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See mtmr9 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (18945057..18986132)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (19044280..19084559)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene XK, Kell blood group complex subunit-related family, member 6b Neighboring gene si:dkey-155d18.1 Neighboring gene L-threonine dehydrogenase Neighboring gene PIN2 (TERF1) interacting telomerase inhibitor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein phosphatase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of autophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylinositol dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    myotubularin-related protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045070.1 → NP_001038535.1  myotubularin-related protein 9

      See identical proteins and their annotated locations for NP_001038535.1

      Status: PROVISIONAL

      Source sequence(s)
      BX510941
      UniProtKB/TrEMBL
      B3DJR1, Q5RHK5
      Related
      ENSDARP00000155110.1, ENSDART00000183632.1
      Conserved Domains (2) summary
      cd13211
      Location:1 → 97
      PH-GRAM_MTMR9; Myotubularian (MTM) related 9 protein (MTMR9) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam06602
      Location:108 → 444
      Myotub-related; Myotubularin-like phosphatase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      18945057..18986132
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160464.5 → XP_005160521.1  myotubularin-related protein 9 isoform X1

      See identical proteins and their annotated locations for XP_005160521.1

      UniProtKB/TrEMBL
      B3DJR1, Q5RHK5
      Related
      ENSDARP00000038320.6, ENSDART00000035447.8
      Conserved Domains (2) summary
      cd13211
      Location:1 → 97
      PH-GRAM_MTMR9; Myotubularian (MTM) related 9 protein (MTMR9) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam06602
      Location:108 → 444
      Myotub-related; Myotubularin-like phosphatase domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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