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    dcaf17 ddb1 and cul4 associated factor 17 [ Danio rerio (zebrafish) ]

    Gene ID: 558828, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dcaf17provided by ZNC
    Official Full Name
    ddb1 and cul4 associated factor 17provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-071008-1
    See related
    Ensembl:ENSDARG00000074909 AllianceGenome:ZFIN:ZDB-GENE-071008-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    c2orf37
    Summary
    Predicted to be involved in protein ubiquitination. Predicted to be located in membrane and nucleolus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Human ortholog(s) of this gene implicated in Woodhouse-Sakati syndrome. Orthologous to human DCAF17 (DDB1 and CUL4 associated factor 17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See dcaf17 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (3499080..3519767, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (3527555..3548188, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene integrin, alpha 6a Neighboring gene cytochrome b reductase 1 Neighboring gene methyltransferase 8, methylcytidine Neighboring gene tousled-like kinase 1a Neighboring gene glutamate decarboxylase 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DDB1- and CUL4-associated factor 17
    Names
    protein C2orf37 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001144789.1 → NP_001138261.1  DDB1- and CUL4-associated factor 17

      See identical proteins and their annotated locations for NP_001138261.1

      Status: PROVISIONAL

      Source sequence(s)
      BX248116
      UniProtKB/Swiss-Prot
      A8WHR0
      Related
      ENSDARP00000121682.1, ENSDART00000145043.3
      Conserved Domains (1) summary
      pfam15802
      Location:44 → 518
      DCAF17; DDB1- and CUL4-associated factor 17

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      3499080..3519767 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223398.1 → XP_068079499.1  DDB1- and CUL4-associated factor 17 isoform X2

      UniProtKB/TrEMBL
      A0A8M6Z2J9

    2. XM_068223397.1 → XP_068079498.1  DDB1- and CUL4-associated factor 17 isoform X2

      UniProtKB/TrEMBL
      A0A8M6Z2J9

    3. XM_068223396.1 → XP_068079497.1  DDB1- and CUL4-associated factor 17 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IWT1, A0A8M6Z0X3

    4. XM_068223395.1 → XP_068079496.1  DDB1- and CUL4-associated factor 17 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IWT1, A0A8M6Z0X3

    5. XM_017357683.3 → XP_017213172.1  DDB1- and CUL4-associated factor 17 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IWT1, A0A8M6Z0X3
      Related
      ENSDARP00000139615.2, ENSDART00000169586.2
      Conserved Domains (1) summary
      pfam15802
      Location:44 → 518
      DCAF17; DDB1- and CUL4-associated factor 17
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8WHR0.1 GenPept UniProtKB/Swiss-Prot:A8WHR0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.