U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    uckl1b uridine-cytidine kinase 1-like 1b [ Danio rerio (zebrafish) ]

    Gene ID: 558466, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    uckl1bprovided by ZNC
    Official Full Name
    uridine-cytidine kinase 1-like 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090311-45
    See related
    Ensembl:ENSDARG00000078973 AllianceGenome:ZFIN:ZDB-GENE-090311-45
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-256k13.1
    Summary
    Predicted to enable ATP binding activity and uridine kinase activity. Predicted to be involved in CTP salvage and UMP salvage. Predicted to act upstream of or within phosphorylation. Orthologous to human UCKL1 (uridine-cytidine kinase 1 like 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See uckl1b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (13528600..13599146)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (13772481..13843079)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene sterile alpha motif domain containing 10b Neighboring gene sb:cb449 Neighboring gene zinc finger protein 512B Neighboring gene uncharacterized LOC103909669 Neighboring gene microRNA mir-1388 Neighboring gene zinc finger and BTB domain containing 46

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Zbtb46 Controls Dendritic Cell Activation by Reprogramming Epigenetic Regulation of cd80/86 and cd40 Costimulatory Signals in a Zebrafish Model. Shao T, et al. J Immunol, 2022 Jun 15. PMID 35675955
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables uridine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in CTP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in UMP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uridine-cytidine kinase-like 1
    Names
    uridine-cytidine kinase 1-like 1
    XP_005162063.1
    XP_005162064.1
    XP_021329253.1
    XP_021329254.1
    XP_068072976.1
    XP_686775.4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      13528600..13599146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_681683.8 → XP_686775.4  uridine-cytidine kinase-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q7P2, A0A8N7TAP2, F1QWG3
      Related
      ENSDARP00000090676.4, ENSDART00000099903.6
      Conserved Domains (3) summary
      COG0572
      Location:81 → 294
      Udk; Uridine kinase [Nucleotide transport and metabolism]
      cd02023
      Location:88 → 287
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:317 → 520
      UPRTase; Uracil phosphoribosyltransferase

    2. XM_005162006.3 → XP_005162063.1  uridine-cytidine kinase-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B8Y1, A0A8M9Q7P2
      Conserved Domains (3) summary
      COG0572
      Location:81 → 294
      Udk; Uridine kinase [Nucleotide transport and metabolism]
      cd02023
      Location:88 → 287
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:318 → 521
      UPRTase; Uracil phosphoribosyltransferase

    3. XM_005162007.5 → XP_005162064.1  uridine-cytidine kinase-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M2B8W6, A0A8M9Q7P2
      Conserved Domains (3) summary
      COG0572
      Location:79 → 292
      Udk; Uridine kinase [Nucleotide transport and metabolism]
      cd02023
      Location:86 → 285
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:316 → 519
      UPRTase; Uracil phosphoribosyltransferase

    4. XM_068216875.1 → XP_068072976.1  uridine-cytidine kinase-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8M9Q7P2

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395133.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      120947..201244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473579.2 → XP_021329254.1  uridine-cytidine kinase-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PWQ5, A0A8M9Q7P2
      Conserved Domains (2) summary
      cd02023
      Location:88 → 287
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:317 → 520
      UPRTase; Uracil phosphoribosyltransferase

    2. XM_021473578.2 → XP_021329253.1  uridine-cytidine kinase-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PQG9, A0A8M9Q7P2
      Conserved Domains (2) summary
      cd02023
      Location:88 → 287
      UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
      pfam14681
      Location:318 → 521
      UPRTase; Uracil phosphoribosyltransferase
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools