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    ube2ql1 ubiquitin conjugating enzyme E2 QL1 [ Danio rerio (zebrafish) ]

    Gene ID: 557472, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ube2ql1provided by ZNC
    Official Full Name
    ubiquitin conjugating enzyme E2 QL1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8137
    See related
    Ensembl:ENSDARG00000079276 AllianceGenome:ZFIN:ZDB-GENE-030131-8137
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj55b04; wu:fj55b04; si:dkey-283j4.1
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to be active in nucleus. Orthologous to human UBE2QL1 (ubiquitin conjugating enzyme E2 QL1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ube2ql1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (27955077..27967068, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (28370854..28383376, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) Neighboring gene NOP2/Sun RNA methyltransferase 2 Neighboring gene mediator complex subunit 10 Neighboring gene uncharacterized LOC137488523

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic Analysis for Differentially Expressed Genes in Ovarian Follicle Activation in the Zebrafish. Zhu B, et al. Front Endocrinol (Lausanne), 2018. PMID 30364302, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme E2Q-like protein 1
    Names
    ubiquitin-conjugating enzyme E2Q family-like 1
    XP_685644.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      27955077..27967068 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_680552.9 → XP_685644.2  ubiquitin-conjugating enzyme E2Q-like protein 1

      UniProtKB/TrEMBL
      A0A8N7TCV3, F1Q4R2
      Related
      ENSDARP00000102172.2, ENSDART00000110016.4
      Conserved Domains (1) summary
      cd00195
      Location:115 → 233
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    Nucleotide Protein Strain
    Heading Accession and Version

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