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    tbc1d10b TBC1 domain family, member 10b [ Danio rerio (zebrafish) ]

    Gene ID: 556457, updated on 4-Jan-2025

    Summary

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    Official Symbol
    tbc1d10bprovided by ZNC
    Official Full Name
    TBC1 domain family, member 10bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7754
    See related
    Ensembl:ENSDARG00000078604 AllianceGenome:ZFIN:ZDB-GENE-030131-7754
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj33d10; wu:fc18f10; wu:fj33d10
    Summary
    Is expressed in nervous system; otic vesicle; and pharyngeal arch. Orthologous to human TBC1D10B (TBC1 domain family member 10B). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See tbc1d10b in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (32786976..32811362)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (32668248..32673661)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene SET domain containing 1A, histone lysine methyltransferase Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase Neighboring gene myosin light chain, phosphorylatable, fast skeletal muscle a Neighboring gene PH domain containing endocytic trafficking adaptor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Embryonic expression patterns of TBC1D10 subfamily genes in zebrafish. Sun S, et al. Gene Expr Patterns, 2022 Mar. PMID 34843939
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    TBC1 domain family member 10B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001365255.1 → NP_001352184.1  TBC1 domain family member 10B isoform 1

      Status: VALIDATED

      Source sequence(s)
      BX571714
      Conserved Domains (2) summary
      smart00164
      Location:331 → 536
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl26464
      Location:8 → 241
      Atrophin-1; Atrophin-1 family

    2. NM_001365256.1 → NP_001352185.1  TBC1 domain family member 10B isoform 2

      Status: VALIDATED

      Source sequence(s)
      BX571714
      Related
      ENSDARP00000130402.1, ENSDART00000171895.2
      Conserved Domains (2) summary
      smart00164
      Location:320 → 525
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl26464
      Location:8 → 241
      Atrophin-1; Atrophin-1 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      32786976..32811362
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217079.1 → XP_068073180.1  TBC1 domain family member 10B isoform X1

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394535.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      270621..292449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395227.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      151470..171884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_023335.2: Suppressed sequence

      Description
      NR_023335.2: This RefSeq was removed because it is now thought that this gene does encode a protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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