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    esd esterase D/formylglutathione hydrolase [ Danio rerio (zebrafish) ]

    Gene ID: 550494, updated on 9-Dec-2024

    Summary

    Official Symbol
    esdprovided by ZNC
    Official Full Name
    esterase D/formylglutathione hydrolaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-328
    See related
    Ensembl:ENSDARG00000019496 AllianceGenome:ZFIN:ZDB-GENE-050417-328
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb58f05; wu:fb58f05; zgc:111984
    Summary
    Predicted to enable S-formylglutathione hydrolase activity. Predicted to act upstream of or within formaldehyde catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in female organism; intestinal bulb; and liver. Orthologous to human ESD (esterase D). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See esd in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (25172101..25181697, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (25361232..25370828, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene rubicon like autophagy enhancer Neighboring gene leucine-rich repeats and calponin homology (CH) domain containing 1 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a Neighboring gene mediator complex subunit 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables S-formylglutathione hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables S-formylglutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within formaldehyde catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    S-formylglutathione hydrolase
    NP_001017796.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017796.2NP_001017796.1  S-formylglutathione hydrolase

      See identical proteins and their annotated locations for NP_001017796.1

      Status: VALIDATED

      Source sequence(s)
      BX323457, EH115372, EH478333, EH605044
      UniProtKB/TrEMBL
      A0A0R4IXM0, A0A8N7XJL5, F6NNG0, Q567K2
      Related
      ENSDARP00000024121.5, ENSDART00000012582.7
      Conserved Domains (2) summary
      PLN02442
      Location:2281
      PLN02442; S-formylglutathione hydrolase
      COG0627
      Location:1282
      FrmB; S-formylglutathione hydrolase FrmB [Defense mechanisms]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      25172101..25181697 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)