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    SLC6A12 solute carrier family 6 member 12 [ Bos taurus (domestic cattle) ]

    Gene ID: 514339, updated on 30-Jan-2025

    Summary

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    Official Symbol
    SLC6A12provided by VGNC
    Official Full Name
    solute carrier family 6 member 12provided by VGNC
    Primary source
    VGNC:VGNC:34915
    See related
    BGD:BT19850; EnsemblRapid:ENSBTAG00070027032
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human all
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    Genomic context

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    See SLC6A12 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (107148265..107167077, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene DEAD/H-box helicase 11 Neighboring gene WASH complex subunit 1 Neighboring gene IQ motif and Sec7 domain ArfGEF 3 Neighboring gene uncharacterized LOC112446765 Neighboring gene solute carrier family 6 member 13 Neighboring gene lysine demethylase 5A Neighboring gene ribosomal protein L27a pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139335

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables gamma-aminobutyric acid:sodium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neurotransmitter transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium- and chloride-dependent betaine transporter
    Names
    solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001434790.1 → NP_001421719.1  sodium- and chloride-dependent betaine transporter

      Status: VALIDATED

      Source sequence(s)
      NKLS02000005
      Related
      ENSBTAP00070036466.1, ENSBTAT00070061293.1

    RNA

    1. NR_197971.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      NKLS02000005

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      107148265..107167077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059886345.1 → XP_059742328.1  sodium- and chloride-dependent betaine transporter isoform X2

    2. XM_059886342.1 → XP_059742325.1  sodium- and chloride-dependent betaine transporter isoform X1

    3. XM_059886343.1 → XP_059742326.1  sodium- and chloride-dependent betaine transporter isoform X1

    4. XM_059886344.1 → XP_059742327.1  sodium- and chloride-dependent betaine transporter isoform X1

    5. XM_015471337.3 → XP_015326823.1  sodium- and chloride-dependent betaine transporter isoform X4

      Conserved Domains (1) summary
      cl00456
      Location:38 → 524
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

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