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    Tatdn2 TatD DNase domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500295, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tatdn2provided by RGD
    Official Full Name
    TatD DNase domain containing 2provided by RGD
    Primary source
    RGD:1586017
    See related
    EnsemblRapid:ENSRNOG00000042482 AllianceGenome:RGD:1586017
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable hydrolase activity, acting on ester bonds. Orthologous to human TATDN2 (TatD DNase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 166.5), Kidney (RPKM 143.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tatdn2 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (148400454..148416501)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (146845156..146865708)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (145653299..145669343)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene von Hippel-Lindau tumor suppressor Neighboring gene uncharacterized LOC120102364 Neighboring gene interleukin-1 receptor-associated kinase 2 Neighboring gene ghrelin and obestatin prepropeptide Neighboring gene SEC13 homolog, nuclear pore and COPII coat complex component

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative deoxyribonuclease TATDN2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109252.1 → NP_001102722.1  putative deoxyribonuclease TATDN2

      See identical proteins and their annotated locations for NP_001102722.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473957
      UniProtKB/TrEMBL
      A6IBT8, D3ZT26
      Related
      ENSRNOP00000097765.2, ENSRNOT00000118522.2
      Conserved Domains (2) summary
      COG1099
      Location:507 → 773
      COG1099; Predicted metal-dependent hydrolase, TIM-barrel fold [General function prediction only]
      pfam01026
      Location:508 → 772
      TatD_DNase; TatD related DNase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      148400454..148416501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010065694.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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