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    Sun3 Sad1 and UNC84 domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498412, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Sun3provided by RGD
    Official Full Name
    Sad1 and UNC84 domain containing 3provided by RGD
    Primary source
    RGD:1591975
    See related
    EnsemblRapid:ENSRNOG00000005105 AllianceGenome:RGD:1591975
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sunc1
    Summary
    Predicted to enable protein-membrane adaptor activity. Predicted to be located in nuclear inner membrane. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in nuclear envelope. Orthologous to human SUN3 (Sad1 and UNC84 domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 60.0), Kidney (RPKM 18.3) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sun3 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (87923891..87962699, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (83710136..83748982, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (89215386..89253585, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene polycystin 1 like 1, transient receptor potential channel interacting Neighboring gene HUS1 checkpoint clamp component Neighboring gene similar to human chromosome 7 open reading frame 57 Neighboring gene uridine phosphorylase 1 Neighboring gene 60S ribosomal protein L35a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mammalian sperm head formation involves different polarization of two novel LINC complexes. Göb E, et al. PLoS One, 2010 Aug 10. PMID 20711465, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein-membrane adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of meiotic nuclear membrane microtubule tethering complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of meiotic nuclear membrane microtubule tethering complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SUN domain-containing protein 3
    Names
    Sad1 and UNC84 domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432834.1 → NP_001419763.1  SUN domain-containing protein 3 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      F1LY77

    2. NM_001432835.1 → NP_001419764.1  SUN domain-containing protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A6KJ85

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      87923891..87962699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006251471.5 → XP_006251533.1  SUN domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006251533.1

      Related
      ENSRNOP00000110120.1, ENSRNOT00000127547.1
      Conserved Domains (1) summary
      pfam07738
      Location:273 → 407
      Sad1_UNC; Sad1 / UNC-like C-terminal

    2. XM_017599513.2 → XP_017455002.1  SUN domain-containing protein 3 isoform X5

      Conserved Domains (1) summary
      pfam07738
      Location:122 → 256
      Sad1_UNC; Sad1 / UNC-like C-terminal

    3. XM_039092857.2 → XP_038948785.1  SUN domain-containing protein 3 isoform X6

      Conserved Domains (1) summary
      pfam07738
      Location:83 → 217
      Sad1_UNC; Sad1 / UNC-like C-terminal

    4. XM_039092856.2 → XP_038948784.1  SUN domain-containing protein 3 isoform X5

      UniProtKB/TrEMBL
      A6KJ85
      Conserved Domains (1) summary
      pfam07738
      Location:122 → 256
      Sad1_UNC; Sad1 / UNC-like C-terminal

    5. XM_008770406.4 → XP_008768628.1  SUN domain-containing protein 3 isoform X3

      Conserved Domains (1) summary
      pfam07738
      Location:182 → 316
      Sad1_UNC; Sad1 / UNC-like C-terminal

    6. XM_017599512.3 → XP_017455001.1  SUN domain-containing protein 3 isoform X2

      Related
      ENSRNOP00000006818.7, ENSRNOT00000006818.7

    7. XM_063273788.1 → XP_063129858.1  SUN domain-containing protein 3 isoform X4

    8. XM_063273789.1 → XP_063129859.1  SUN domain-containing protein 3 isoform X7

    RNA

    1. XR_005493415.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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