cyp2b6.L cytochrome P450 family 2 subfamily B member 6 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cyp2b6.L
Official Full Name: cytochrome P450 family 2 subfamily B member 6 L homeolog
Primary source: Xenbase:XB-GENE-6466088
Locus tag: XELAEV_18028189mg
See related: EnsemblRapid:ENSXLAG00005009144 AllianceGenome:Xenbase:XB-GENE-6466088
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: cyp2b6
Summary: Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; drug dependence (multiple); human immunodeficiency virus infectious disease; neonatal abstinence syndrome; and nicotine dependence. Orthologous to human CYP2B6 (cytochrome P450 family 2 subfamily B member 6). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

Location:: chromosome: 5L

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5L	NC_054379.1 (160337792..160351897, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5L	NC_030732.1 (149291943..149306061, complement)

Chromosome 5L - NC_054379.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome P450 family 2 subfamily B member 6 L homeolog

Names: cytochrome P450, family 2, subfamily B, polypeptide 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094630.1 → NP_001088099.1 cytochrome P450 family 2 subfamily B member 6 L homeolog precursor

See identical proteins and their annotated locations for NP_001088099.1

Status: PROVISIONAL

Source sequence(s)

BC082928

UniProtKB/TrEMBL

A0A974CZ00, Q63ZI7

Related

ENSXLAP00005026621.1, ENSXLAT00005027353.1

Conserved Domains (1) summary

pfam00067
Location:31 → 484

p450; Cytochrome P450

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

160337792..160351897 complement

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GenBank, FASTA, Sequence Viewer (Graphics)