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    guaA glutamine-hydrolyzing GMP synthase [ Mycobacterium canettii CIPT 140010059 ]

    Gene ID: 45427392, updated on 11-Dec-2024

    Summary

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    Gene symbol
    guaA
    Gene description
    glutamine-hydrolyzing GMP synthase
    Locus tag
    MCAN_RS17985
    Gene type
    protein coding
    Organism
    Mycobacterium canettii CIPT 140010059 (strain: CIPT 140010059)
    Lineage
    Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    Old locus tag
    MCAN_34201
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    Genomic context

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    Sequence:
    NC_015848.1 (3879816..3881393, complement)

    NC_015848.1Genomic Context describing neighboring genes Neighboring gene DNA polymerase Y family protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene presqualene diphosphate synthase HpnD Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_015848.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families. Tesmer JJ, et al. Nat Struct Biol, 1996 Jan. PMID 8548458
    2. Preliminary X-ray analysis of Escherichia coli GMP synthetase: determination of anomalous scattering factors for a cysteinyl mercury derivative. Tesmer JJ, et al. Proteins, 1994 Apr. PMID 8208731
    3. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Supply P, et al. Nat Genet, 2013 Feb. PMID 23291586, Free PMC Article
    4. The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex. Bentley SD, et al. PLoS Negl Trop Dis, 2012. PMID 22389744, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    glutamine-hydrolyzing GMP synthase
    WP_003417952.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_015848.1 Reference assembly

      Range
      3879816..3881393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_003417952.1 MULTISPECIES: glutamine-hydrolyzing GMP synthase [Mycobacterium]

      See identical proteins and their annotated locations for WP_003417952.1

      UniProtKB/Swiss-Prot
      A0A1R3Y480, A1KP87, A5U871, C1AHL0, P0A5A2, P9WMS7, Q50729, X2BPF9
      UniProtKB/TrEMBL
      A0A045I7P2, A0A679LKQ9, A0A7V9WJ76, A0A829CAL8, A0A9P2M5P7, A0AAU0Q866, A0AAW8I6C2, A0AAX1PRA0
      Conserved Domains (1) summary
      PRK00074
      Location:15 → 525
      guaA; GMP synthase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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