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    PRAMEF25 PRAME family member 25 [ Homo sapiens (human) ]

    Gene ID: 441873, updated on 10-Dec-2024

    Summary

    Official Symbol
    PRAMEF25provided by HGNC
    Official Full Name
    PRAME family member 25provided by HGNC
    Primary source
    HGNC:HGNC:49179
    See related
    Ensembl:ENSG00000229571 AllianceGenome:HGNC:49179
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to be involved in several processes, including negative regulation of DNA-templated transcription; negative regulation of apoptotic process; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See PRAMEF25 in Genome Data Viewer
    Location:
    1p36.21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (13070774..13077884)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (12589589..12596703)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 27 Neighboring gene heterogeneous nuclear ribonucleoprotein C like 3 Neighboring gene PRAME family member 34, pseudogene Neighboring gene PRAME family member 35, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    PRAME family member 25
    Names
    putative PRAME family member 25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310134.3NP_001297063.1  PRAME family member 25

      See identical proteins and their annotated locations for NP_001297063.1

      Status: INFERRED

      Source sequence(s)
      AC245056
      Consensus CDS
      CCDS81265.1
      UniProtKB/Swiss-Prot
      A6NGN4, H0Y7S4
      UniProtKB/TrEMBL
      B7ZW04
      Related
      ENSP00000478309.2, ENST00000619661.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      13070774..13077884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_012132914.1 Reference GRCh38.p14 PATCHES

      Range
      225114..232224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_015495298.1 Reference GRCh38.p14 PATCHES

      Range
      66390..73500
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      12589589..12596703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)