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    side sidestep [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43300, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sideprovided by FlyBase
    Official Full Name
    sidestepprovided by FlyBase
    Primary source
    FLYBASE:FBgn0016061
    Locus tag
    Dmel_CG31062
    See related
    AllianceGenome:FB:FBgn0016061
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12510; CG13973; CG13974; CG13975; CG13979; CG31062; CT33527; CT33528; Dmel\CG31062; doe; Doe; Side
    Summary
    Involved in motor neuron axon guidance. Is expressed in adult head; larval central nervous system; larval muscle system; lobula columnar neuron LC14; and midline. Orthologous to human VSIG10L (V-set and immunoglobulin domain containing 10 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See side in Genome Data Viewer
    Location:
    97F6-98A1; 3-93 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27375088..27437482, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23200810..23263204, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43476 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45991 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. guidance errors in sidestep mutants are maintained throughout larval life and are asymmetrical with respect to the bilateral body axis.
      Title: Sidestep-induced neuromuscular miswiring causes severe locomotion defects in Drosophila larvae.
    2. motor axons recognize and follow Side-expressing cell surfaces from the ventral nerve cord to their target region
      Title: Drosophila motor axons recognize and follow a Sidestep-labeled substrate pathway to reach their target fields.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in motor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sidestep
    Names
    CG31062-PA
    CG31062-PB
    CG31062-PC
    CG31062-PD
    downstream of eyeless
    side-PA
    side-PB
    side-PC
    side-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27375088..27437482 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144645.3 → NP_001138117.1  sidestep, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138117.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0R1, Q967X6
      Conserved Domains (5) summary
      smart00410
      Location:435 → 511
      IG_like; Immunoglobulin like
      cd00063
      Location:700 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07686
      Location:95 → 211
      V-set; Immunoglobulin V-set domain
      pfam13895
      Location:442 → 511
      Ig_2; Immunoglobulin domain
      cl11960
      Location:326 → 408
      Ig; Immunoglobulin domain

    2. NM_001260406.2 → NP_001247335.1  sidestep, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247335.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K6K0, Q967X6
      Conserved Domains (5) summary
      smart00410
      Location:435 → 511
      IG_like; Immunoglobulin like
      cd00063
      Location:700 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07686
      Location:95 → 211
      V-set; Immunoglobulin V-set domain
      pfam13895
      Location:442 → 511
      Ig_2; Immunoglobulin domain
      cl11960
      Location:326 → 408
      Ig; Immunoglobulin domain

    3. NM_001260405.2 → NP_001247334.1  sidestep, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247334.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K7N1, Q967X6
      Conserved Domains (5) summary
      smart00410
      Location:435 → 511
      IG_like; Immunoglobulin like
      cd00063
      Location:700 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07686
      Location:95 → 211
      V-set; Immunoglobulin V-set domain
      pfam13895
      Location:442 → 511
      Ig_2; Immunoglobulin domain
      cl11960
      Location:326 → 408
      Ig; Immunoglobulin domain

    4. NM_079806.4 → NP_524530.2  sidestep, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524530.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q967X6, Q9VB35
      Related
      FBpp0084538
      Conserved Domains (5) summary
      smart00410
      Location:435 → 511
      IG_like; Immunoglobulin like
      cd00063
      Location:700 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07686
      Location:95 → 211
      V-set; Immunoglobulin V-set domain
      pfam13895
      Location:442 → 511
      Ig_2; Immunoglobulin domain
      cl11960
      Location:326 → 408
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K6K0 A0A0B4K6K0
    A0A0B4K7N1 A0A0B4K7N1
    B7Z0R1 B7Z0R1
    Q967X6 Q967X6
    Q9VB35 Q9VB35

    Gene LinkOut

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