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    Ndc1 Nuclear division cycle 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42825, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ndc1provided by FlyBase
    Official Full Name
    Nuclear division cycle 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0039125
    Locus tag
    Dmel_CG5857
    See related
    AllianceGenome:FB:FBgn0039125
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5857; Dmel\CG5857; ndc1; NDC1
    Summary
    Predicted to enable protein-macromolecule adaptor activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nuclear pore complex assembly. Located in endomembrane system. Is expressed in adult head and organism. Orthologous to human NDC1 (NDC1 transmembrane nucleoporin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ndc1 in Genome Data Viewer
    Location:
    95C12-95C13; 3-81 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23924399..23926436)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19750121..19752158)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene six-banded Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Regulatory particle triple-A ATPase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Topology of yeast Ndc1p: predictions for the human NDC1/NET3 homologue. Lau CK, et al. Anat Rec A Discov Mol Cell Evol Biol, 2006 Jul. PMID 16779818, Free PMC Article
    2. Identification of potential pathways and biomarkers linked to progression in ALS. Huber RG, et al. Ann Clin Transl Neurol, 2023 Feb. PMID 36533811, Free PMC Article
    3. Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Hampoelz B, et al. Cell, 2019 Oct 17. PMID 31626769, Free PMC Article
    4. Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila. Raza Q, et al. PLoS Genet, 2019 Feb. PMID 30763317, Free PMC Article
    5. Comparative genomic evidence for a complete nuclear pore complex in the last eukaryotic common ancestor. Neumann N, et al. PLoS One, 2010 Oct 8. PMID 20949036, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear pore complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in nuclear pore organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    part_of nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of nuclear pore transmembrane ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nuclear division cycle 1
    Names
    CG5857-PA
    Ndc1 ortholog
    Ndc1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23924399..23926436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142934.4 → NP_651191.1  nuclear division cycle 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651191.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3YE69, Q9VCG4
      Related
      FBpp0083879
      Conserved Domains (1) summary
      pfam09531
      Location:63 → 571
      Ndc1_Nup; Nucleoporin protein Ndc1-Nup
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VCG4.1 Q9VCG4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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