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    KLHL8 kelch like family member 8 [ Gallus gallus (chicken) ]

    Gene ID: 422589, updated on 17-Aug-2024

    Summary

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    Symbol
    KLHL8provided by CGNC
    Full Name
    kelch like family member 8provided by CGNC
    Primary source
    CGNC:8373
    See related
    Ensembl:ENSGALG00010003816
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See KLHL8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (45302755..45319098)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (45242866..45259143)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110561 Neighboring gene nudix hydrolase 9 Neighboring gene hydroxysteroid 17-beta dehydrogenase 13 Neighboring gene uncharacterized LOC107051737 Neighboring gene AF4/FMR2 family member 1 Neighboring gene protein tyrosine phosphatase, non-receptor type 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kelch-like protein 8
    Names
    kelch-like 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      45302755..45319098
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046941309.1 → XP_046797265.1  kelch-like protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEQ2

    2. XM_046941310.1 → XP_046797266.1  kelch-like protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEQ2

    3. XM_046941308.1 → XP_046797264.1  kelch-like protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEQ2

    4. XM_040700222.2 → XP_040556156.1  kelch-like protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEQ2
      Related
      ENSGALP00010005173.1, ENSGALT00010008829.1
      Conserved Domains (5) summary
      smart00612
      Location:585 → 629
      Kelch; Kelch domain
      PHA03098
      Location:57 → 565
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:353 → 396
      Kelch; KELCH repeat [structural motif]
      cd18238
      Location:49 → 168
      BTB_POZ_KLHL8; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 8 (KLHL8)
      cd18448
      Location:160 → 256
      BACK_KLHL8; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 8 (KLHL8)

    5. XM_015276505.4 → XP_015131991.1  kelch-like protein 8 isoform X2

      UniProtKB/TrEMBL
      A0A1D5NW05, E1BQR4
      Related
      ENSGALP00010005174.1, ENSGALT00010008830.1
      Conserved Domains (3) summary
      smart00612
      Location:552 → 596
      Kelch; Kelch domain
      PHA03098
      Location:57 → 532
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:353 → 396
      Kelch; KELCH repeat [structural motif]

    6. XM_046941307.1 → XP_046797263.1  kelch-like protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEQ2

    7. XM_040700223.2 → XP_040556157.1  kelch-like protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEQ2
      Conserved Domains (5) summary
      smart00612
      Location:585 → 629
      Kelch; Kelch domain
      PHA03098
      Location:57 → 565
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:353 → 396
      Kelch; KELCH repeat [structural motif]
      cd18238
      Location:49 → 168
      BTB_POZ_KLHL8; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 8 (KLHL8)
      cd18448
      Location:160 → 256
      BACK_KLHL8; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 8 (KLHL8)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      45242866..45259143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046917561.1 → XP_046773517.1  kelch-like protein 8 isoform X1

    2. XM_046917560.1 → XP_046773516.1  kelch-like protein 8 isoform X1

    3. XM_040669686.2 → XP_040525620.1  kelch-like protein 8 isoform X2

      Conserved Domains (4) summary
      smart00612
      Location:552 → 596
      Kelch; Kelch domain
      PHA03098
      Location:57 → 532
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:353 → 396
      Kelch; KELCH repeat [structural motif]
      cd18238
      Location:49 → 168
      BTB_POZ_KLHL8; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 8 (KLHL8)

    4. XM_040669685.2 → XP_040525619.1  kelch-like protein 8 isoform X1

      Conserved Domains (5) summary
      smart00612
      Location:585 → 629
      Kelch; Kelch domain
      PHA03098
      Location:57 → 565
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:353 → 396
      Kelch; KELCH repeat [structural motif]
      cd18238
      Location:49 → 168
      BTB_POZ_KLHL8; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 8 (KLHL8)
      cd18448
      Location:160 → 256
      BACK_KLHL8; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 8 (KLHL8)
    Nucleotide Protein
    Heading Accession and Version

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