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    PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Gallus gallus (chicken) ]

    Gene ID: 419444, updated on 3-Dec-2024

    Summary

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    Symbol
    PIK3CDprovided by CGNC
    Full Name
    phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit deltaprovided by CGNC
    Primary source
    CGNC:1859
    See related
    Ensembl:ENSGALG00010017035
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PIK3CD in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (3443409..3489188)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (3476786..3522483)

    Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 33 Neighboring gene transmembrane protein 201 Neighboring gene forkhead box protein D1 Neighboring gene calsyntenin 1 Neighboring gene uncharacterized LOC121107382 Neighboring gene catenin beta interacting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
    Names
    phosphoinositide-3-kinase, catalytic, delta polypeptide
    NP_001012714.2
    XP_015152374.1
    XP_024998287.1
    XP_046787227.1
    XP_046787228.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012696.2 → NP_001012714.2  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000329
      UniProtKB/TrEMBL
      F1NHX1, Q5F3P4
      Related
      ENSGALP00010024069.1, ENSGALT00010041133.1
      Conserved Domains (5) summary
      cd08693
      Location:315 → 481
      C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
      smart00145
      Location:504 → 687
      PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
      cd05174
      Location:679 → 1044
      PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
      pfam00794
      Location:182 → 280
      PI3K_rbd; PI3-kinase family, ras-binding domain
      pfam02192
      Location:32 → 107
      PI3K_p85B; PI3-kinase family, p85-binding domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      3443409..3489188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015296888.3 → XP_015152374.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

      UniProtKB/TrEMBL
      F1NHX1, Q5F3P4
      Conserved Domains (5) summary
      cd08693
      Location:315 → 481
      C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
      smart00145
      Location:504 → 687
      PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
      cd05174
      Location:679 → 1044
      PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
      pfam00794
      Location:182 → 280
      PI3K_rbd; PI3-kinase family, ras-binding domain
      pfam02192
      Location:32 → 107
      PI3K_p85B; PI3-kinase family, p85-binding domain

    2. XM_025142519.3 → XP_024998287.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

      UniProtKB/TrEMBL
      F1NHX1, Q5F3P4
      Conserved Domains (5) summary
      cd08693
      Location:315 → 481
      C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
      smart00145
      Location:504 → 687
      PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
      cd05174
      Location:679 → 1044
      PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
      pfam00794
      Location:182 → 280
      PI3K_rbd; PI3-kinase family, ras-binding domain
      pfam02192
      Location:32 → 107
      PI3K_p85B; PI3-kinase family, p85-binding domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      3476786..3522483
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046931271.1 → XP_046787227.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

      UniProtKB/TrEMBL
      F1NHX1, Q5F3P4

    2. XM_046931272.1 → XP_046787228.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

      UniProtKB/TrEMBL
      F1NHX1, Q5F3P4
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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