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    SHROOM2 shroom family member 2 [ Gallus gallus (chicken) ]

    Gene ID: 418651, updated on 3-Dec-2024

    Summary

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    Symbol
    SHROOM2provided by CGNC
    Full Name
    shroom family member 2provided by CGNC
    Primary source
    CGNC:12449
    See related
    Ensembl:ENSGALG00010002194
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    APXL
    Orthologs
    human mouse all
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    Genomic context

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    See SHROOM2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (125171927..125294627, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (125126794..125249666, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101749389 Neighboring gene uncharacterized LOC112531501 Neighboring gene claudin 34 Neighboring gene G protein-coupled receptor 143 Neighboring gene transducin beta like X1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in apical junction complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cortical actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein Shroom2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      125171927..125294627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025146614.3 → XP_025002382.2  protein Shroom2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEZ7
      Related
      ENSGALP00010002952.1, ENSGALT00010004931.1
      Conserved Domains (1) summary
      cd00992
      Location:35 → 115
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    2. XM_004938410.5 → XP_004938467.4  protein Shroom2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XBL1, A0A8V0XBL6
      Related
      ENSGALP00010002953.1, ENSGALT00010004933.1
      Conserved Domains (1) summary
      smart00228
      Location:52 → 110
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

    3. XM_046909433.1 → XP_046765389.1  protein Shroom2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEZ1

    4. XM_046909447.1 → XP_046765403.1  protein Shroom2 isoform X5

    5. XM_046909437.1 → XP_046765393.1  protein Shroom2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0XBK7
      Related
      ENSGALP00010002942.1, ENSGALT00010004911.1

    6. XM_025146616.3 → XP_025002384.1  protein Shroom2 isoform X5

      Conserved Domains (1) summary
      pfam08687
      Location:153 → 447
      ASD2; Apx/Shroom domain ASD2

    7. XM_040662498.2 → XP_040518432.1  protein Shroom2 isoform X5

      Conserved Domains (1) summary
      pfam08687
      Location:153 → 447
      ASD2; Apx/Shroom domain ASD2

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      125126794..125249666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040659462.2 → XP_040515396.1  protein Shroom2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XEZ7
      Conserved Domains (1) summary
      cd00992
      Location:35 → 115
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    2. XM_040659464.2 → XP_040515398.1  protein Shroom2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XBL1
      Conserved Domains (1) summary
      smart00228
      Location:52 → 110
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

    3. XM_046909398.1 → XP_046765354.1  protein Shroom2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XEZ1

    4. XM_046909400.1 → XP_046765356.1  protein Shroom2 isoform X5

    5. XM_046909399.1 → XP_046765355.1  protein Shroom2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0XBK7

    6. XM_040659466.2 → XP_040515400.1  protein Shroom2 isoform X5

    7. XM_040659465.2 → XP_040515399.1  protein Shroom2 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials