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    AKAP13 A-kinase anchoring protein 13 [ Gallus gallus (chicken) ]

    Gene ID: 415502, updated on 3-Dec-2024

    Summary

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    Official Symbol
    AKAP13provided by CGNC
    Official Full Name
    A-kinase anchoring protein 13provided by CGNC
    Primary source
    CGNC:49999
    See related
    Ensembl:ENSGALG00010020117
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See AKAP13 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (13984259..14178852, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (13861993..14056682, complement)

    Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene neurotrophic receptor tyrosine kinase 3 Neighboring gene uncharacterized LOC107054206 Neighboring gene uncharacterized LOC112533196 Neighboring gene ATP/GTP binding protein like 1 Neighboring gene kelch like family member 25 Neighboring gene uncharacterized LOC121111581 Neighboring gene synaptic vesicle glycoprotein 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables MAP-kinase scaffold activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adrenergic receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A-kinase anchor protein 13
    Names
    A kinase (PRKA) anchor protein 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      13984259..14178852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046899348.1 → XP_046755304.1  A-kinase anchor protein 13 isoform X8

      UniProtKB/TrEMBL
      A0A8V0Z609

    2. XM_046899343.1 → XP_046755299.1  A-kinase anchor protein 13 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z621

    3. XM_046899346.1 → XP_046755302.1  A-kinase anchor protein 13 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z609
      Related
      ENSGALP00010028692.1, ENSGALT00010048601.1

    4. XM_046899344.1 → XP_046755300.1  A-kinase anchor protein 13 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z616

    5. XM_046899347.1 → XP_046755303.1  A-kinase anchor protein 13 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Z621

    6. XM_046899342.1 → XP_046755298.1  A-kinase anchor protein 13 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z621

    7. XM_046899345.1 → XP_046755301.1  A-kinase anchor protein 13 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z621, A0A8V0ZBV8
      Related
      ENSGALP00010028699.1, ENSGALT00010048608.1

    8. XM_046899337.1 → XP_046755293.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    9. XM_046899338.1 → XP_046755294.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    10. XM_046899339.1 → XP_046755295.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    11. XM_046899340.1 → XP_046755296.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    12. XM_046899349.1 → XP_046755305.1  A-kinase anchor protein 13 isoform X9

      UniProtKB/TrEMBL
      A0A8V0Z621

    13. XM_046899350.1 → XP_046755306.1  A-kinase anchor protein 13 isoform X10

      UniProtKB/TrEMBL
      A0A8V0Z621

    14. XM_046899352.1 → XP_046755308.1  A-kinase anchor protein 13 isoform X12

      UniProtKB/TrEMBL
      A0A8V0ZJA6
      Related
      ENSGALP00010028683.1, ENSGALT00010048593.1

    15. XM_046899353.1 → XP_046755309.1  A-kinase anchor protein 13 isoform X12

      UniProtKB/TrEMBL
      A0A8V0ZJA6

    16. XM_040706420.2 → XP_040562354.1  A-kinase anchor protein 13 isoform X15

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Conserved Domains (6) summary
      COG1196
      Location:877 → 1221
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1115 → 1223
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:547 → 741
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:784 → 886
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1090 → 1311
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:347 → 387
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    17. XM_040706419.2 → XP_040562353.1  A-kinase anchor protein 13 isoform X14

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Related
      ENSGALP00010028674.1, ENSGALT00010048583.1
      Conserved Domains (6) summary
      COG1196
      Location:929 → 1273
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1167 → 1275
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:599 → 793
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:836 → 938
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1142 → 1363
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:399 → 439
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    18. XM_040706418.2 → XP_040562352.1  A-kinase anchor protein 13 isoform X13

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Related
      ENSGALP00010028676.1, ENSGALT00010048585.1
      Conserved Domains (6) summary
      COG1196
      Location:930 → 1274
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1168 → 1276
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:600 → 794
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:837 → 939
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1143 → 1364
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:400 → 440
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    19. XM_040706417.2 → XP_040562351.1  A-kinase anchor protein 13 isoform X11

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Conserved Domains (6) summary
      COG1196
      Location:969 → 1313
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1207 → 1315
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:639 → 833
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:876 → 978
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1182 → 1403
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:439 → 479
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    20. XM_025154078.3 → XP_025009846.2  A-kinase anchor protein 13 isoform X16

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      13861993..14056682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046925084.1 → XP_046781040.1  A-kinase anchor protein 13 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z609

    2. XM_046925076.1 → XP_046781032.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    3. XM_046925086.1 → XP_046781042.1  A-kinase anchor protein 13 isoform X8

      UniProtKB/TrEMBL
      A0A8V0Z609

    4. XM_046925079.1 → XP_046781035.1  A-kinase anchor protein 13 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z621

    5. XM_046925083.1 → XP_046781039.1  A-kinase anchor protein 13 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z609

    6. XM_046925081.1 → XP_046781037.1  A-kinase anchor protein 13 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z616

    7. XM_046925085.1 → XP_046781041.1  A-kinase anchor protein 13 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Z621

    8. XM_046925078.1 → XP_046781034.1  A-kinase anchor protein 13 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z621

    9. XM_046925082.1 → XP_046781038.1  A-kinase anchor protein 13 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z621

    10. XM_046925073.1 → XP_046781029.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    11. XM_046925074.1 → XP_046781030.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    12. XM_046925075.1 → XP_046781031.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    13. XM_046925077.1 → XP_046781033.1  A-kinase anchor protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z621

    14. XM_046925087.1 → XP_046781043.1  A-kinase anchor protein 13 isoform X9

      UniProtKB/TrEMBL
      A0A8V0Z621

    15. XM_046925088.1 → XP_046781044.1  A-kinase anchor protein 13 isoform X10

      UniProtKB/TrEMBL
      A0A8V0Z621

    16. XM_046925089.1 → XP_046781045.1  A-kinase anchor protein 13 isoform X12

      UniProtKB/TrEMBL
      A0A8V0ZJA6

    17. XM_046925091.1 → XP_046781047.1  A-kinase anchor protein 13 isoform X12

      UniProtKB/TrEMBL
      A0A8V0ZJA6

    18. XM_040679824.2 → XP_040535758.1  A-kinase anchor protein 13 isoform X15

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Conserved Domains (6) summary
      COG1196
      Location:877 → 1221
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1115 → 1223
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:547 → 741
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:784 → 886
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1090 → 1311
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:347 → 387
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    19. XM_040679822.2 → XP_040535756.1  A-kinase anchor protein 13 isoform X14

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Conserved Domains (6) summary
      COG1196
      Location:929 → 1273
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1167 → 1275
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:599 → 793
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:836 → 938
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1142 → 1363
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:399 → 439
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    20. XM_040679821.2 → XP_040535755.1  A-kinase anchor protein 13 isoform X13

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Conserved Domains (6) summary
      COG1196
      Location:930 → 1274
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1168 → 1276
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:600 → 794
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:837 → 939
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1143 → 1364
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:400 → 440
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    21. XM_040679820.2 → XP_040535754.1  A-kinase anchor protein 13 isoform X11

      UniProtKB/TrEMBL
      A0A8V0ZBT3
      Conserved Domains (6) summary
      COG1196
      Location:969 → 1313
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:1207 → 1315
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:639 → 833
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:876 → 978
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam17380
      Location:1182 → 1403
      DUF5401; Family of unknown function (DUF5401)
      cl00040
      Location:439 → 479
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    22. XM_040679825.2 → XP_040535759.1  A-kinase anchor protein 13 isoform X16

    Nucleotide Protein Strain
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