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    med22 mediator complex subunit 22 [ Danio rerio (zebrafish) ]

    Gene ID: 415234, updated on 9-Dec-2024

    Summary

    Official Symbol
    med22provided by ZNC
    Official Full Name
    mediator complex subunit 22provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-156
    See related
    Ensembl:ENSDARG00000014148 AllianceGenome:ZFIN:ZDB-GENE-040625-156
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    surf5; zgc:86721; wu:fj45h07; si:dkey-226m8.2; si:ch73-278c20.1
    Summary
    Predicted to enable transcription coregulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Orthologous to human MED22 (mediator complex subunit 22). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See med22 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (33287628..33295554)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32687458..32695434)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD24 Neighboring gene small nucleolar RNA SNORD24 Neighboring gene ribosomal protein L7a Neighboring gene zgc:103692 Neighboring gene ubiquitin specific peptidase 20

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 22
    Names
    surfeit 5
    surfeit locus protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002144.1NP_001002144.1  mediator of RNA polymerase II transcription subunit 22

      See identical proteins and their annotated locations for NP_001002144.1

      Status: PROVISIONAL

      Source sequence(s)
      BC071397
      UniProtKB/TrEMBL
      A0A8M9PXA1
      Related
      ENSDARP00000109672.2, ENSDART00000125093.4
      Conserved Domains (1) summary
      pfam06179
      Location:20124
      Med22; Surfeit locus protein 5 subunit 22 of Mediator complex

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      33287628..33295554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171831.3XP_005171888.1  mediator of RNA polymerase II transcription subunit 22 isoform X1

      See identical proteins and their annotated locations for XP_005171888.1

      UniProtKB/Swiss-Prot
      A5WUL3, Q6IQK8
      UniProtKB/TrEMBL
      A0A8M2BJ43, F1QGP2
      Related
      ENSDARP00000111825.1, ENSDART00000123210.3
      Conserved Domains (1) summary
      pfam06179
      Location:20124
      Med22; Surfeit locus protein 5 subunit 22 of Mediator complex