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    CG6923 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41420, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6923provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037944
    Locus tag
    Dmel_CG6923
    See related
    AllianceGenome:FB:FBgn0037944
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6923
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be active in cytosol. Is expressed in wing hinge primordium and wing pouch. Orthologous to human RNF111 (ring finger protein 111). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6923 in Genome Data Viewer
    Location:
    86E17-86E17; 3-51 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11744229..11750029, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7569951..7575751, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Bloom syndrome helicase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Lk6 kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Lk6 kinase controls phosphorylation of eukaryotic translation initiation factor 4E and promotes normal growth and development. Arquier N, et al. Curr Biol, 2005 Jan 11. PMID 15649359
    2. A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning. Ketosugbo KF, et al. PLoS One, 2017. PMID 29117266, Free PMC Article
    3. Genetic annotation of gain-of-function screens using RNA interference and in situ hybridization of candidate genes in the Drosophila wing. Molnar C, et al. Genetics, 2012 Oct. PMID 22798488, Free PMC Article
    4. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article
    5. Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. Lindsey ARI, et al. mBio, 2021 Feb 9. PMID 33563832, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6923-PA
    CG6923-PB
    CG6923-PC
    CG6923-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11744229..11750029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141855.4 → NP_650112.1  uncharacterized protein Dmel_CG6923, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650112.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWE3, Q9VGI6
      Related
      FBpp0081908
      Conserved Domains (2) summary
      pfam12678
      Location:1185 → 1228
      zf-rbx1; RING-H2 zinc finger
      pfam13639
      Location:1187 → 1228
      zf-RING_2; Ring finger domain

    2. NM_001260127.1 → NP_001247056.1  uncharacterized protein Dmel_CG6923, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247056.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWE3, Q9VGI6
      Conserved Domains (2) summary
      pfam12678
      Location:1185 → 1228
      zf-rbx1; RING-H2 zinc finger
      pfam13639
      Location:1187 → 1228
      zf-RING_2; Ring finger domain

    3. NM_001275555.2 → NP_001262484.1  uncharacterized protein Dmel_CG6923, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262484.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFN6, Q6AWE3
      Conserved Domains (2) summary
      pfam12678
      Location:1185 → 1228
      zf-rbx1; RING-H2 zinc finger
      pfam13639
      Location:1187 → 1228
      zf-RING_2; Ring finger domain

    4. NM_169422.2 → NP_731623.1  uncharacterized protein Dmel_CG6923, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731623.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWE3, Q9VGI6
      Related
      FBpp0081909
      Conserved Domains (2) summary
      pfam12678
      Location:1185 → 1228
      zf-rbx1; RING-H2 zinc finger
      pfam13639
      Location:1187 → 1228
      zf-RING_2; Ring finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFN6 A0A0B4KFN6
    Q9VGI6 Q9VGI6

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