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    Elovl7 ELOVL fatty acid elongase 7 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40943, updated on 9-Dec-2024

    Summary

    Official Symbol
    Elovl7provided by FlyBase
    Official Full Name
    ELOVL fatty acid elongase 7provided by FlyBase
    Primary source
    FLYBASE:FBgn0037534
    Locus tag
    Dmel_CG2781
    See related
    AllianceGenome:FB:FBgn0037534
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2781; dELOVL; Dmel\CG2781; ELOVL
    Summary
    Predicted to enable fatty acid elongase activity. Involved in long-chain fatty acid metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult fat body; embryonic dorsal epidermis; embryonic epipharynx; embryonic head epidermis; and gut section. Used to study adrenoleukodystrophy. Orthologous to human ELOVL1 (ELOVL fatty acid elongase 1) and ELOVL7 (ELOVL fatty acid elongase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Elovl7 in Genome Data Viewer
    Location:
    84E6-84E7; 3-48 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (7981817..7995852, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (3807539..3821574, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene CD98 heavy chain Neighboring gene Os-C Neighboring gene Seminal fluid protein 84E Neighboring gene long non-coding RNA:CR46143 Neighboring gene long non-coding RNA:CR46142

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fatty acid elongase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables fatty acid elongase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid elongation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in fatty acid elongation, monounsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid elongation, polyunsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid elongation, saturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in long-chain fatty acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sphingolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in very long-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ELOVL fatty acid elongase 7
    Names
    CG2781-PA
    ELOVL fatty acid elongase
    Elovl7-PA
    NP_649754.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      7981817..7995852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141497.2NP_649754.1  ELOVL fatty acid elongase 7 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649754.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8MS02, Q9VHX7
      Related
      FBpp0081313
      Conserved Domains (1) summary
      pfam01151
      Location:27266
      ELO; GNS1/SUR4 family