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    orc5 origin recognition complex, subunit 5 [ Danio rerio (zebrafish) ]

    Gene ID: 406479, updated on 9-Dec-2024

    Summary

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    Official Symbol
    orc5provided by ZNC
    Official Full Name
    origin recognition complex, subunit 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2275
    See related
    Ensembl:ENSDARG00000021579 AllianceGenome:ZFIN:ZDB-GENE-040426-2275
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    orc5l; zgc:77827; wu:fb62d08
    Summary
    Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication initiation. Predicted to act upstream of or within DNA replication. Predicted to be located in nucleus. Predicted to be part of nuclear origin of replication recognition complex. Orthologous to human ORC5 (origin recognition complex subunit 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See orc5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (22353467..22363718, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (22632492..22658389, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene golgin B1 Neighboring gene uncharacterized LOC101884046 Neighboring gene uncharacterized LOC137491547 Neighboring gene guanylate cyclase activator 1Aa Neighboring gene LHFPL tetraspan subfamily member 3 Neighboring gene lysine (K)-specific methyltransferase 2E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Telomerase Is Essential for Zebrafish Heart Regeneration. Bednarek D, et al. Cell Rep, 2015 Sep 8. PMID 26321646, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA replication origin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA replication initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear origin of replication recognition complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of origin recognition complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    origin recognition complex subunit 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213198.1 → NP_998363.1  origin recognition complex subunit 5

      See identical proteins and their annotated locations for NP_998363.1

      Status: PROVISIONAL

      Source sequence(s)
      BC065383
      UniProtKB/TrEMBL
      A0A8M6Z5W8, Q6P0X9
      Related
      ENSDARP00000033056.4, ENSDART00000037670.5
      Conserved Domains (2) summary
      pfam13191
      Location:21 → 164
      AAA_16; AAA ATPase domain
      pfam14630
      Location:187 → 440
      ORC5_C; Origin recognition complex (ORC) subunit 5 C-terminus

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      22353467..22363718 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017354989.3 → XP_017210478.1  origin recognition complex subunit 5 isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z5W8, Q6P0X9
      Conserved Domains (2) summary
      pfam13191
      Location:21 → 164
      AAA_16; AAA ATPase domain
      pfam14630
      Location:187 → 440
      ORC5_C; Origin recognition complex (ORC) subunit 5 C-terminus

    2. XM_021474980.2 → XP_021330655.1  origin recognition complex subunit 5 isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z5W8, Q6P0X9
      Conserved Domains (2) summary
      pfam13191
      Location:21 → 164
      AAA_16; AAA ATPase domain
      pfam14630
      Location:187 → 440
      ORC5_C; Origin recognition complex (ORC) subunit 5 C-terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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