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    fancg FA complementation group G [ Danio rerio (zebrafish) ]

    Gene ID: 402936, updated on 9-Dec-2024

    Summary

    Official Symbol
    fancgprovided by ZNC
    Official Full Name
    FA complementation group Gprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-103
    See related
    Ensembl:ENSDARG00000024967 AllianceGenome:ZFIN:ZDB-GENE-050417-103
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:109717
    Summary
    Predicted to be involved in DNA damage response. Predicted to act upstream of or within interstrand cross-link repair. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gonad; heart; nervous system; oral epithelium; and rostral blood island. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group G; and pancreatic cancer. Orthologous to human FANCG (FA complementation group G). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See fancg in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (41496594..41509315)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (40896441..40909162)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene protein inhibitor of activated STAT, 2 Neighboring gene eukaryotic translation elongation factor 2, like 2 Neighboring gene valosin containing protein Neighboring gene aldo-keto reductase family 1, member A1a (aldehyde reductase)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    Fanconi anemia group G protein
    Names
    Fanconi anemia G
    Fanconi anemia, complementation group G

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205639.1NP_991202.1  Fanconi anemia group G protein

      See identical proteins and their annotated locations for NP_991202.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ496390
      UniProtKB/TrEMBL
      Q70YH6
      Related
      ENSDARP00000038408.3, ENSDART00000039369.4
      Conserved Domains (2) summary
      sd00006
      Location:451491
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:514576
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      41496594..41509315
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395242.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      264851..278937
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)