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    cyp2p10 cytochrome P450, family 2, subfamily P, polypeptide 10 [ Danio rerio (zebrafish) ]

    Gene ID: 399485, updated on 9-Dec-2024

    Summary

    Official Symbol
    cyp2p10provided by ZNC
    Official Full Name
    cytochrome P450, family 2, subfamily P, polypeptide 10provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040120-1
    See related
    Ensembl:ENSDARG00000042990 AllianceGenome:ZFIN:ZDB-GENE-040120-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cyp2j21; cyp2j2a
    Summary
    Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including nervous system; neural plate; neural rod; neural tube; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypertension (multiple); myocardial infarction; and renal fibrosis. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cyp2p10 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (25586235..25593607)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (25687145..25694611)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily P, polypeptide 8 Neighboring gene cytochrome P450, family 2, subfamily P, polypeptide 9 Neighboring gene cytochrome P450, family 2, subfamily J, polypeptide 20 Neighboring gene uncharacterized LOC110438177 Neighboring gene uncharacterized LOC137488651

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in organic acid metabolic process  
    involved_in xenobiotic metabolic process  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    is_active_in intracellular membrane-bounded organelle  
    located_in membrane  

    General protein information

    Preferred Names
    cytochrome P450 2P10
    Names
    cytochrome P450, family 2, subfamily J, polypeptide 2, A
    cytochrome P450, family 2, subfamily J, polypeptide 21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201511.1 → NP_958919.1  cytochrome P450 2P10

      See identical proteins and their annotated locations for NP_958919.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049521
      UniProtKB/TrEMBL
      Q7ZU60
      Related
      ENSDARP00000063121.4, ENSDART00000063122.5
      Conserved Domains (1) summary
      pfam00067
      Location:38 → 493
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      25586235..25593607
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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