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    minpp1b multiple inositol-polyphosphate phosphatase 1b [ Danio rerio (zebrafish) ]

    Gene ID: 394075, updated on 9-Dec-2024

    Summary

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    Official Symbol
    minpp1bprovided by ZNC
    Official Full Name
    multiple inositol-polyphosphate phosphatase 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-888
    See related
    Ensembl:ENSDARG00000045172 AllianceGenome:ZFIN:ZDB-GENE-040426-888
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    minpp1; zgc:56080; zgc:76991
    Summary
    Predicted to enable acid phosphatase activity and inositol phosphate phosphatase activity. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma and pontocerebellar hypoplasia type 16. Orthologous to human MINPP1 (multiple inositol-polyphosphate phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See minpp1b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (17482607..17492822, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (17360733..17370998, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene ATPase family AAA domain containing 1b Neighboring gene 3'-phosphoadenosine 5'-phosphosulfate synthase 2b Neighboring gene cytohesin 3a Neighboring gene uncharacterized LOC137496809 Neighboring gene ubiquitin specific peptidase 42 Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC56080

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acid phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables bisphosphoglycerate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol hexakisphosphate 2-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol phosphate phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables inositol-hexakisphosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    multiple inositol polyphosphate phosphatase 1b
    Names
    multiple inositol polyphosphate histidine phosphatase, 1
    multiple inositol polyphosphate histidine phosphatase, 1b
    NP_957394.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201100.1 → NP_957394.1  multiple inositol polyphosphate phosphatase 1b precursor

      See identical proteins and their annotated locations for NP_957394.1

      Status: PROVISIONAL

      Source sequence(s)
      BC047824
      UniProtKB/TrEMBL
      Q7ZUU7
      Related
      ENSDARP00000016794.7, ENSDART00000012421.9
      Conserved Domains (1) summary
      pfam00328
      Location:71 → 409
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      17482607..17492822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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