poglut2 protein O-glucosyltransferase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: poglut2provided by ZNC
Official Full Name: protein O-glucosyltransferase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-878
See related: Ensembl:ENSDARG00000031971 AllianceGenome:ZFIN:ZDB-GENE-040426-878
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Kdel1; kdelc1; zgc:56065
Summary: Predicted to enable UDP-glucosyltransferase activity and UDP-xylosyltransferase activity. Predicted to be involved in protein O-linked glycosylation via serine. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endomembrane system. Orthologous to human POGLUT2 (protein O-glucosyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (27398328..27410513, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (27587582..27599767, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables EGF-domain serine glucosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables EGF-domain serine xylosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables UDP-glucosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables UDP-xylosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables glucosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables hexosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables pentosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in nervous system development	IEA Inferred from Electronic Annotation more info
involved_in protein O-linked glycosylation via serine	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum lumen	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein O-glucosyltransferase 2

Names: KDEL (Lys-Asp-Glu-Leu) containing 1; KDEL motif-containing protein 1; protein O-xylosyltransferase POGLUT2

NP_957225.1

EC 2.4.2.26

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200931.1 → NP_957225.1 protein O-glucosyltransferase 2 precursor

See identical proteins and their annotated locations for NP_957225.1

Status: PROVISIONAL

Source sequence(s)

BC045893

UniProtKB/Swiss-Prot

B0CM11, Q5RI39, Q7ZVE6

Related

ENSDARP00000042296.5, ENSDART00000042297.7

Conserved Domains (2) summary

pfam00630
Location:33 → 126

Filamin; Filamin/ABP280 repeat

pfam05686
Location:147 → 500

Glyco_transf_90; Glycosyl transferase family 90