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    rnf181 ring finger protein 181 [ Danio rerio (zebrafish) ]

    Gene ID: 393276, updated on 9-Dec-2024

    Summary

    Official Symbol
    rnf181provided by ZNC
    Official Full Name
    ring finger protein 181provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1024
    See related
    Ensembl:ENSDARG00000023958 AllianceGenome:ZFIN:ZDB-GENE-040426-1024
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56424
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be active in cytoplasm. Orthologous to human RNF181 (ring finger protein 181). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See rnf181 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (26756002..26764925, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (26155849..26164772, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene transport and golgi organization 2 homolog (Drosophila) Neighboring gene transmembrane protein 150Aa Neighboring gene si:ch211-102c2.8 Neighboring gene coiled-coil domain containing 117

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC56424

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF181
    Names
    RING-type E3 ubiquitin transferase RNF181
    NP_956600.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200306.1NP_956600.1  E3 ubiquitin-protein ligase RNF181

      See identical proteins and their annotated locations for NP_956600.1

      Status: PROVISIONAL

      Source sequence(s)
      BC050161
      UniProtKB/Swiss-Prot
      B0V3A5, B0V3A6, Q7ZW78
      Related
      ENSDARP00000038991.4, ENSDART00000029450.6
      Conserved Domains (1) summary
      pfam13639
      Location:79120
      zf-RING_2; Ring finger domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      26756002..26764925 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)