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    CG7387 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38915, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG7387provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035852
    Locus tag
    Dmel_CG7387
    See related
    AllianceGenome:FB:FBgn0035852
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.72; Dmel\CG7387
    Summary
    Predicted to enable heat shock protein binding activity and unfolded protein binding activity. Predicted to be involved in mitochondrion organization. Predicted to be active in mitochondrion. Is expressed in spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7387 in Genome Data Viewer
    Location:
    66B11-66B11; 3-22 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8191522..8193116, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8184622..8186216, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45870 Neighboring gene estrogen-related receptor Neighboring gene Autophagy-related 18a Neighboring gene Mediator complex subunit 24 Neighboring gene NEDD8-conjugating enzyme UbcE2M Neighboring gene Deoxyhypusine synthase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington's disease related aggregates. Deo A, et al. Sci Rep, 2024 Sep 6. PMID 39242711, Free PMC Article
    2. RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology. Raut S, et al. G3 (Bethesda), 2017 Jul 5. PMID 28500055, Free PMC Article
    3. A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network. Lunardi A, et al. Proc Natl Acad Sci U S A, 2010 Apr 6. PMID 20308539, Free PMC Article
    4. Mettl3-dependent m(6)A modification attenuates the brain stress response in Drosophila. Perlegos AE, et al. Nat Commun, 2022 Sep 14. PMID 36104353, Free PMC Article
    5. Genome-wide measurement of spatial expression in patterning mutants of Drosophila melanogaster. Combs PA, et al. F1000Res, 2017. PMID 28299188, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7387-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8191522..8193116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139929.4 → NP_648186.3  uncharacterized protein Dmel_CG7387 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648186.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0AMW9, Q8SZX1, Q9VSF1
      Related
      FBpp0076446
      Conserved Domains (4) summary
      cd10719
      Location:233 → 296
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
      cd10747
      Location:298 → 416
      DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
      TIGR02349
      Location:101 → 431
      DnaJ_bact; chaperone protein DnaJ
      pfam00226
      Location:101 → 161
      DnaJ; DnaJ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZX1 Q8SZX1

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