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    postna periostin, osteoblast specific factor a [ Danio rerio (zebrafish) ]

    Gene ID: 378983, updated on 4-Jan-2025

    Summary

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    Official Symbol
    postnaprovided by ZNC
    Official Full Name
    periostin, osteoblast specific factor aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091113-23
    See related
    Ensembl:ENSDARG00000043806 AllianceGenome:ZFIN:ZDB-GENE-091113-23
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb925; si:dkey-109i21.1; si:ch211-250c16.2
    Summary
    Is expressed in caudal fin skeleton; digestive system; epidermis; and pronephros. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human POSTN (periostin). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See postna in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (25762196..25816606, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (25800483..25855078, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene SR-related CTD-associated factor 4a Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide D1 Neighboring gene finTRIM family, member 54 Neighboring gene transient receptor potential cation channel, subfamily C, member 4a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Differential reparative phenotypes between zebrafish and medaka after cardiac injury. Ito K, et al. Dev Dyn, 2014 Sep. PMID 24947076
    2. Inhibition of let-7c Regulates Cardiac Regeneration after Cryoinjury in Adult Zebrafish. Narumanchi S, et al. J Cardiovasc Dev Dis, 2019 Apr 4. PMID 30987331, Free PMC Article
    3. CHD7 regulates craniofacial cartilage development via controlling HTR2B expression. Breuer M, et al. J Bone Miner Res, 2024 May 2. PMID 38477756, Free PMC Article
    4. Midkine-a Regulates the Formation of a Fibrotic Scar During Zebrafish Heart Regeneration. Grivas D, et al. Front Cell Dev Biol, 2021. PMID 34026760, Free PMC Article
    5. Functional Heterogeneity within the Developing Zebrafish Epicardium. Weinberger M, et al. Dev Cell, 2020 Mar 9. PMID 32084358, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    periostin; periostin, osteoblast specific factor a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      25762196..25816606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002663548.6 → XP_002663594.2  periostin

      UniProtKB/TrEMBL
      A0A8M1RKG7
      Related
      ENSDARP00000018627.8, ENSDART00000017240.9
      Conserved Domains (2) summary
      COG2335
      Location:461 → 635
      FAS1; Uncaracterized surface protein containing fasciclin (FAS1) repeats [General function prediction only]
      pfam02469
      Location:245 → 367
      Fasciclin; Fasciclin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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