U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Ip6k Inositol hexakisphosphate kinase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37465, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ip6kprovided by FlyBase
    Official Full Name
    Inositol hexakisphosphate kinaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034644
    Locus tag
    Dmel_CG10082
    See related
    AllianceGenome:FB:FBgn0034644
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.149; CG10082; Dmel\CG10082; dmIP6K
    Summary
    Predicted to enable inositol hexakisphosphate kinase activity. Predicted to be involved in inositol phosphate biosynthetic process and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including amnioserosa; ganglia; glial cell; gut section; and hypodermal muscle cell of A1-7. Orthologous to human IP6K1 (inositol hexakisphosphate kinase 1); IP6K2 (inositol hexakisphosphate kinase 2); and IP6K3 (inositol hexakisphosphate kinase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ip6k in Genome Data Viewer
    Location:
    57F6-57F6; 2-96 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21646177..21657935)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17533682..17545440)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR42547 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43786 Neighboring gene NADH dehydrogenase (ubiquinone) B12 subunit Neighboring gene Rae1 Neighboring gene poor Imd response upon knock-in

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables inositol hexakisphosphate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables inositol hexakisphosphate kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in inositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in inositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phosphatidylinositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphatidylinositol phosphate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    inositol hexakisphosphate kinase
    Names
    3-hydroxyisobutyryl-CoA hydrolase
    CG10082-PA
    CG10082-PB
    Ip6k-PA
    Ip6k-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21646177..21657935
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166466.3NP_726095.2  inositol hexakisphosphate kinase, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726095.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2E9
      Related
      FBpp0071578
      Conserved Domains (2) summary
      pfam03770
      Location:303450
      IPK; Inositol polyphosphate kinase
      cl12283
      Location:821894
      IPK; Inositol polyphosphate kinase
    2. NM_137751.4NP_611595.3  inositol hexakisphosphate kinase, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611595.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRK4, Q961X0
      Related
      FBpp0071579
      Conserved Domains (2) summary
      pfam03770
      Location:73220
      IPK; Inositol polyphosphate kinase
      cl12283
      Location:591664
      IPK; Inositol polyphosphate kinase