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    Cep20 centrosomal protein 20 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360461, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cep20provided by RGD
    Official Full Name
    centrosomal protein 20provided by RGD
    Primary source
    RGD:1305823
    See related
    AllianceGenome:RGD:1305823
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fopnl; RGD1305823
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in cilium assembly. Predicted to be located in centriolar satellite and nucleoplasm. Predicted to be active in centrosome; ciliary basal body; and motile cilium. Orthologous to human CEP20 (centrosomal protein 20). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 198.2), Muscle (RPKM 148.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cep20 in Genome Data Viewer
    Location:
    10q11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (1221294..1243144)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (714051..736826)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (730215..751061)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene aurora kinase A, pseudogene 1 Neighboring gene ATP binding cassette subfamily C member 1 Neighboring gene ribosomal protein S3a, pseudogene 8 Neighboring gene myosin heavy chain 11 Neighboring gene nudE neurodevelopment protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Control of ciliogenesis by FOR20, a novel centrosome and pericentriolar satellite protein. Sedjaï F, et al. J Cell Sci, 2010 Jul 15. PMID 20551181
    2. The sequence and analysis of duplication-rich human chromosome 16. Martin J, et al. Nature, 2004 Dec 23. PMID 15616553
    3. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in microtubule anchoring IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in motile cilium ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    centrosomal protein 20
    Names
    FGFR1OP N-terminal like
    lisH domain-containing protein FOPNL

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108261.1 → NP_001101731.1  centrosomal protein 20

      See identical proteins and their annotated locations for NP_001101731.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474126
      UniProtKB/TrEMBL
      A0A0G2JYM1, B0BN31
      Conserved Domains (1) summary
      pfam09398
      Location:43 → 113
      FOP_dimer; FOP N terminal dimerization domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      1221294..1243144
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006245848.5 → XP_006245910.1  centrosomal protein 20 isoform X1

      Conserved Domains (1) summary
      pfam09398
      Location:43 → 113
      FOP_dimer; FOP N terminal dimerization domain

    2. XM_039086246.2 → XP_038942174.1  centrosomal protein 20 isoform X2

      Conserved Domains (1) summary
      cl29685
      Location:43 → 89
      LisH_2

    3. XM_039086247.2 → XP_038942175.1  centrosomal protein 20 isoform X3

      Conserved Domains (1) summary
      cl29685
      Location:43 → 98
      LisH_2
    Nucleotide Protein Strain
    Heading Accession and Version

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