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    T04A8.7 1,4-alpha-glucan branching enzyme [ Caenorhabditis elegans ]

    Gene ID: 3565201, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T04A8.7
    Official Full Name
    1,4-alpha-glucan branching enzyme
    Primary source
    WormBase:WBGene00011409
    Locus tag
    CELE_T04A8.7
    See related
    AllianceGenome:WB:WBGene00011409
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 1,4-alpha-glucan branching enzyme activity. Predicted to be involved in glycogen biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease IV and pulmonary tuberculosis. Orthologous to human GBE1 (1,4-alpha-glucan branching enzyme 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T04A8.7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (4695357..4698014)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Amidophosphoribosyltransferase Neighboring gene RRM domain-containing protein Neighboring gene Rad60/SUMO-like domain-containing protein Neighboring gene J domain-containing protein Neighboring gene Zinc finger protein 830

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Duchaine TF, et al. Cell, 2006 Jan 27. PMID 16439208
    2. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article
    3. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
    4. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 1,4-alpha-glucan branching enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 1,4-alpha-glucan branching enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cation binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycogen biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycogen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    1,4-alpha-glucan branching enzyme
    NP_497961.1
    • Confirmed by transcript evidence
    NP_871631.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4695357..4698014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_181902.3 → NP_871631.1  1,4-alpha-glucan branching enzyme [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_871631.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86G92
      Conserved Domains (1) summary
      PLN02447
      Location:11 → 606
      PLN02447; 1,4-alpha-glucan-branching enzyme

    2. NM_065560.7 → NP_497961.1  1,4-alpha-glucan branching enzyme [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497961.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22137
      Conserved Domains (1) summary
      PLN02447
      Location:1 → 681
      PLN02447; 1,4-alpha-glucan-branching enzyme
    Nucleotide Protein
    Heading Accession and Version

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