Sps2 Selenophosphate synthetase 2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Sps2provided by FlyBase
Official Full Name: Selenophosphate synthetase 2provided by FlyBase
Primary source: FLYBASE:FBgn0032224
Locus tag: Dmel_CG5025
See related: AllianceGenome:FB:FBgn0032224
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG5025; Dmel\CG5025; dsps2; dSPS2; Dsps2; sps2; SPS2
Summary: Predicted to enable purine nucleotide binding activity and selenide, water dikinase activity. Predicted to be involved in selenocysteine biosynthetic process. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic/larval gut; female germline cell; midgut primordium; and presumptive embryonic/larval system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (10342594..10344223)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (10342594..10344223)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

the transcriptome of fruit flies with knockdown of SPS2 in larval and adult stages, is reported.[Sps2]
Title: Gene expression profiling of selenophosphate synthetase 2 knockdown in Drosophila melanogaster.
The downstream DNA replication-related element has been identified as an essential element for dsps2 promoter activity.
Title: A DNA replication-related element downstream from the initiation site of Drosophila selenophosphate synthetase 2 gene is essential for its transcription.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP binding	TAS Traceable Author Statement more info	PubMed
enables purine nucleotide binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables selenide, water dikinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables selenide, water dikinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in selenocysteine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in selenocysteine biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

NP_001260329.1

NP_477478.4

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The following sections contain reference sequences that belong to a specific genome build. Explain