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    Oatp26F Organic anion transporting polypeptide 26F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33927, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Oatp26Fprovided by FlyBase
    Official Full Name
    Organic anion transporting polypeptide 26Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051634
    Locus tag
    Dmel_CG31634
    See related
    AllianceGenome:FB:FBgn0051634
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11332; CG13767; CG18784; CG31634; Dmel\CG31634; oatp 26F; oatp26F
    Summary
    Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport and transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in several structures, including ganglia; larval nervous system; mesectoderm; midline primordium; and ventral midline of embryo. Orthologous to human SLCO4A1 (solute carrier organic anion transporter family member 4A1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Oatp26F in Genome Data Viewer
    Location:
    26F3-26F3; 2-21 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6625138..6632407, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6625138..6632407, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44913 Neighboring gene Dpr-interacting protein iota Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Transport and Golgi organization 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Essential functions of mosquito ecdysone importers in development and reproduction. Hun LV, et al. Proc Natl Acad Sci U S A, 2022 Jun 21. PMID 35696563, Free PMC Article
    2. Resolution of the insect ouabain paradox. Torrie LS, et al. Proc Natl Acad Sci U S A, 2004 Sep 14. PMID 15347816, Free PMC Article
    3. Common motifs shared by conserved enhancers of Drosophila midline glial genes. Fulkerson E, et al. J Exp Zool B Mol Dev Evol, 2011 Jan 15. PMID 21154525
    4. An Oatp transporter-mediated steroid sink promotes tumor-induced cachexia in Drosophila. Santabárbara-Ruiz P, et al. Dev Cell, 2021 Oct 11. PMID 34610327
    5. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Okamoto N, et al. Dev Cell, 2018 Nov 5. PMID 30293839, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables organic anion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables sodium-independent organic anion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in organic anion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in sodium-independent organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    organic anion transporting polypeptide 26F
    Names
    CG31634-PA
    Oatp26F-PA
    organic anion transporter protein 26f

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6625138..6632407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135211.3 → NP_609055.2  organic anion transporting polypeptide 26F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609055.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY02, Q9I7P0
      Related
      FBpp0078956
      Conserved Domains (3) summary
      cd06174
      Location:69 → 318
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:476 → 529
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      pfam03137
      Location:66 → 647
      OATP; Organic Anion Transporter Polypeptide (OATP) family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SY02 Q8SY02

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