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    CG1801 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33104, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1801provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031171
    Locus tag
    Dmel_CG1801
    See related
    AllianceGenome:FB:FBgn0031171
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    DmCG1801; Dmel\CG1801
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Orthologous to human ABCA13 (ATP binding cassette subfamily A member 13). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1801 in Genome Data Viewer
    Location:
    19F3-19F4; 1-65 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21307586..21317522, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21178613..21188549, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 3 Neighboring gene transfer RNA:Tyrosine-GTA 1-1 Neighboring gene transfer RNA:Tyrosine-GTA 2-1 Neighboring gene Regulatory particle triple-A ATPase 6 Neighboring gene SRA stem-loop interacting RNA binding protein 1 Neighboring gene anorexia Neighboring gene Dullard

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP-Binding Cassette (ABC) Transporter Genes Involved in Pyrethroid Resistance in the Malaria Vector Anopheles sinensis: Genome-Wide Identification, Characteristics, Phylogenetics, and Expression Profile. He Q, et al. Int J Mol Sci, 2019 Mar 20. PMID 30897799, Free PMC Article
    2. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Ren Q, et al. Nucleic Acids Res, 2007 Jan. PMID 17135193, Free PMC Article
    3. The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance. Dermauw W, et al. Insect Biochem Mol Biol, 2014 Feb. PMID 24291285
    4. The human ATP-binding cassette (ABC) transporter superfamily. Dean M, et al. Genome Res, 2001 Jul. PMID 11435397
    5. Whole-genome expression analysis in the third instar larval midgut of Drosophila melanogaster. Harrop TW, et al. G3 (Bethesda), 2014 Sep 5. PMID 25193493, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c21309984-21309523 mobile_element_type = transposon:INE-1{}6145
    • Loc: c21315869-21315457 mobile_element_type = transposon:INE-1{}6146

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables lipid transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1801-PC
    NP_728408.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      21307586..21317522 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167739.3 → NP_728408.3  uncharacterized protein Dmel_CG1801 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728408.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRG5
      Conserved Domains (4) summary
      COG1122
      Location:499 → 717
      EcfA2; Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only]
      pfam12698
      Location:972 → 1254
      ABC2_membrane_3; ABC-2 family transporter protein
      pfam12730
      Location:293 → 448
      ABC2_membrane_4; ABC-2 family transporter protein
      cl21455
      Location:1324 → 1524
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRG5 Q9VRG5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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