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    ints14 integrator complex subunit 14 [ Danio rerio (zebrafish) ]

    Gene ID: 327593, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ints14provided by ZNC
    Official Full Name
    integrator complex subunit 14provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5804
    See related
    Ensembl:ENSDARG00000041429 AllianceGenome:ZFIN:ZDB-GENE-030131-5804
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    vwa9; fi19c12; zgc:55794; wu:fi19c12
    Summary
    Predicted to be involved in snRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Orthologous to human INTS14 (integrator complex subunit 14). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ints14 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (18995247..19005877, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (19006181..19017193, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene si:dkey-73n10.1 Neighboring gene phosphopantothenoylcysteine decarboxylase Neighboring gene 3-hydroxyacyl-CoA dehydratase 3 Neighboring gene solute carrier family 24 member 1 Neighboring gene DENN/MADD domain containing 4A Neighboring gene si:dkey-242h9.5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation of ints14 Knockout Zebrafish using CRISPR/Cas9 for the Study of Development and Disease Mechanisms. Jung JH, et al. Dev Reprod, 2023 Dec. PMID 38292235, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of integrator complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    integrator complex subunit 14
    Names
    von Willebrand factor A domain containing 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199834.1 → NP_956128.1  integrator complex subunit 14

      See identical proteins and their annotated locations for NP_956128.1

      Status: PROVISIONAL

      Source sequence(s)
      BC048891
      UniProtKB/TrEMBL
      A0A8M1PDI9, Q7ZUK5
      Related
      ENSDARP00000111847.2, ENSDART00000129776.3
      Conserved Domains (1) summary
      cd00198
      Location:4 → 137
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      18995247..19005877 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159052.5 → XP_005159109.1  integrator complex subunit 14 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B5I4, Q1LWK5
      Related
      ENSDARP00000060730.3, ENSDART00000060731.5
      Conserved Domains (1) summary
      cd00198
      Location:4 → 137
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395020.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      279013..290533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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