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    larp1 La ribonucleoprotein 1, translational regulator [ Danio rerio (zebrafish) ]

    Gene ID: 327175, updated on 4-Jan-2025

    Summary

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    Official Symbol
    larp1provided by ZNC
    Official Full Name
    La ribonucleoprotein 1, translational regulatorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5386
    See related
    Ensembl:ENSDARG00000101722 AllianceGenome:ZFIN:ZDB-GENE-030131-5386
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb92d03; wu:fd15e07
    Summary
    Predicted to enable RNA cap binding activity. Predicted to act upstream of or within mRNA stabilization. Orthologous to human LARP1 (La ribonucleoprotein 1, translational regulator). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See larp1 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (45855156..45872099, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (45816637..45834474, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene fatty acid hydroxylase domain containing 2 Neighboring gene uncharacterized LOC137488853 Neighboring gene thioredoxin domain containing 15 Neighboring gene sap30-like Neighboring gene UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA cap binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA stabilization IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    la-related protein 1B; la-related protein 1
    Names
    La ribonucleoprotein domain family, member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      45855156..45872099 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001920867.9 → XP_001920902.3  la-related protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M1QKI5
      Related
      ENSDARP00000137117.2, ENSDART00000161716.2
      Conserved Domains (3) summary
      smart00684
      Location:825 → 863
      DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
      cd08037
      Location:310 → 382
      LARP_1; La RNA-binding domain of La-related protein 1
      PHA03089
      Location:109 → 161
      PHA03089; late transcription factor VLTF-4; Provisional

    2. XM_021469267.2 → XP_021324942.1  la-related protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9P457
      Conserved Domains (2) summary
      smart00684
      Location:831 → 869
      DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
      cd08037
      Location:310 → 382
      LARP_1; La RNA-binding domain of La-related protein 1
    Nucleotide Protein Strain
    Heading Accession and Version

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