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    hang hangover [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32613, updated on 9-Dec-2024

    Summary

    Official Symbol
    hangprovided by FlyBase
    Official Full Name
    hangoverprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026575
    Locus tag
    Dmel_CG32575
    See related
    AllianceGenome:FB:FBgn0026575
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM07804; BcDNA:LD22118; CG32575; CG4411; CG4416; Dmel\CG32575; Hang; HANG; LD22118
    Summary
    Enables mRNA binding activity. Involved in several processes, including behavioral response to ethanol; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; and response to heat. Located in nucleus. Is expressed in several structures, including brain; epithelium; follicle cell; head epidermis primordium; and mesoderm. Used to study alcohol use disorder. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See hang in Genome Data Viewer
    Location:
    14C4-14C4; 1-53 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16422831..16438454)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16316864..16332487)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene TNF-receptor-associated factor-like Neighboring gene Annexin B11 Neighboring gene Cell division cycle 50 Neighboring gene rings lost Neighboring gene eukaryotic translation initiation factor 2 subunit alpha

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    hangover
    Names
    CG32575-PA
    CG32575-PC
    CG32575-PD
    hang-PA
    hang-PC
    hang-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16422831..16438454
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144732.2NP_001138204.1  hangover, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138204.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0Z1
      Conserved Domains (3) summary
      sd00017
      Location:14201440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:12791298
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:80154
      zf-AD; Zinc-finger associated domain (zf-AD)
    2. NM_167520.3NP_727979.3  hangover, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727979.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VXG1, Q9VXG2
      Conserved Domains (2) summary
      sd00017
      Location:11561176
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:80154
      zf-AD; Zinc-finger associated domain (zf-AD)
    3. NM_167521.3NP_727980.2  hangover, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727980.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VXG1
      Conserved Domains (3) summary
      sd00017
      Location:11521172
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:10111030
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:80154
      zf-AD; Zinc-finger associated domain (zf-AD)